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The knowledge acquisition bottleneck in the development of large knowledge based applications has not yet been resolved. One approach which has been advocated is the systematic use of Machine Learning (ML) techniques. However, ML technology poses difficulties to domain experts and knowledge engineers who are not familiar with it. This paper discusses(More)
Decision support systems (DSS) that are simple, spatial, flexible, non-deterministic and have a long track record of practical application in a policy environment have until recently been uncommon. There has been a rapid expansion in the development and description of both quantitative and soft system methods that can be applied to decision-making processes(More)
Well-type ionization chamber is often used to measure strength of brachytherapy sources. This study aims to check long term response stability of High Dose Rate (HDR)-1000 Plus well-type ionization chamber in terms of reference air kerma rate (RAKR) of a reference (137)Cs brachytherapy source and recommend an optimum frequency of recalibration. An HDR-1000(More)
The Machine Learning Toolbox c o n tains a set of ten Machine Learning algorithms , integrated with a common interface and common knowledge representation language. An essential component o f t h e T oolbox is the Consultant, a knowledge-based system that advises novice users about which algorithm they could use for a particular application. We show h o w(More)
Radiation-induced heart disease (RIHD) is a long-term side effect of radiotherapy of intrathoracic, chest wall and breast tumors when radiation fields encompass all or part of the heart. Previous studies have shown that pentoxifylline (PTX) in combination with α-tocopherol reduced manifestations of RIHD in rat models of local heart irradiation. The relative(More)
In radiotherapy treatment of thoracic, breast and chest wall tumors, the heart may be included (partially or fully) in the radiation field. As a result, patients may develop radiation-induced heart disease (RIHD) several years after exposure to radiation. There are few methods available to prevent or reverse RIHD and the biological mechanisms remain poorly(More)