Sunil K. Sinha

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BACKGROUND/AIMS Sex steroids, such as estrogens, are known to influence endothelial function by their vasodilator action. The aim of this study was to study the relation of puberty and sex steroids with endothelial function using peripheral arterial tonometry (PAT). METHODS In 89 healthy school boys and girls, we determined height, weight, waist(More)
Buried infrastructures like sewers and water mains have to be checked for their current condition. Cracks are a strong indicator for the condition of a pipe. An affordable way to detect those cracks is to take images of the pipeline and use image processing techniques to detect cracks in these images. The methods used to accomplish this task are(More)
The enormity of the problem of deteriorating pipeline infrastructure is widely apparent. Since a complete rebuilding of the piping system is not financially realistic, municipal and utility operators require the ability to monitor the condition of buried pipes. Thus, reliable pipeline assessment and management tools are necessary to develop long term cost(More)
Pipeline surface defects such as holes and cracks cause major problems for utility managers, particularly when the pipeline is buried under the ground. Manual inspection for surface defects in the pipeline has a number of drawbacks, including subjectivity, varying standards, and high costs. Automatic inspection system using image processing and artificial(More)
BACKGROUND Management of oral anticoagulation in patients undergoing pacemaker (PPM) or implantable cardioverter-defibrillator (ICD) implantation remains controversial. Prior studies demonstrate that continuation of warfarin may be safer when compared with strategies requiring interruption and/or heparin bridging. Limited data from randomized trials exist.(More)
OBJECTIVES This study was designed to assess the risk of significant bleeding complications in patients receiving antiplatelet or anticoagulation medications at the time of implantable cardioverter-defibrillator (ICD) device implantation. BACKGROUND Periprocedural management of antiplatelet or anticoagulation therapy at the time of device implantation(More)
OBJECTIVES We examined the possible effect of neuropeptide Y in modulating central sympathetic activity after myocardial infarction in rats. BACKGROUND Previous studies have shown the coexistence of neuropeptide Y and norepinephrine in the brain and a possible functional interaction between the two. Neuropeptide Y inhibits the release of norepinephrine at(More)
OBJECTIVES This study sought to evaluate the outcomes of radiofrequency catheter ablation (RFA) of ventricular tachycardia (VT) in arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) patients. Particular focus was placed on defining the single-procedure efficacy over long-term follow-up. BACKGROUND ARVD/C is an inherited cardiomyopathy(More)
BACKGROUND Although it is well recognized that recovery of pulmonary vein (PV) conduction is common among patients who fail atrial fibrillation (AF) ablation, little is known about the precise time course of recurrence. OBJECTIVE To determine the incidence and time course of early recurrence of conduction after PV isolation during AF ablation. METHODS(More)
BACKGROUND The reported complication rate of catheter ablation of atrial fibrillation (AF) varies. OBJECTIVE Our goal was to assess temporal trends and the effect of both institutional and individual operators' experience on the incidence of complications. METHODS All patients undergoing AF ablation at Johns Hopkins Hospital between February 2001 and(More)