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Anti-inflammatory effects of magnolol and honokiol are mediated through inhibition of the downstream pathway of MEKK-1 in NF-kappaB activation signaling.

• Jongsung Lee, E Jung, +8 authors Deokhoon Park
• Planta medica
• 2005

Propionibacterium acnes, an anaerobic pathogen, plays an important role in the pathogenesis of acne and seems to initiate the inflammatory process by producing proinflammatory cytokines. In order to… (More)

Asiaticoside induces human collagen I synthesis through TGFbeta receptor I kinase (TbetaRI kinase)-independent Smad signaling.

• Jongsung Lee, E Jung, +7 authors Deokhoon Park
• Planta medica
• 2006

Skin aging appears to be principally related to a decrease in the levels of type I collagen, the primary component of the skin dermis. Asiaticoside, a saponin component isolated from Centella… (More)

Glycyrrhizin induces melanogenesis by elevating a cAMP level in b16 melanoma cells.

• Jongsung Lee, E Jung, +8 authors Deokhoon Park
• The Journal of investigative dermatology
• 2005

In mammalian melanocytes, melanin synthesis is controlled by tyrosinase, the critical enzyme in the melanogenic pathway. A recent report showed that the stimulation of melanogenesis by glycyrrhizin… (More)

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