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Nictation, a dispersal behavior of the nematode Caenorhabditis elegans, is regulated by IL2 neurons
It is demonstrated that nictation is required for transmission of C. elegans to a new niche using flies as artificial carriers, suggesting a role of nietation as a dispersal and survival strategy under harsh conditions.
Enhanced Caenorhabditis elegans Locomotion in a Structured Microfluidic Environment
- Sungsu Park, Hyejin Hwang, Seong-Won Nam, F. Martinez, R. Austin, W. Ryu
- Biology, EngineeringPloS one
- 25 June 2008
These results show that the microstructure can be used as a behavioral screen for mechanosensory and uncoordinated mutants, and it is likely that worms use mechanosensation in the movement and navigation through heterogeneous environments.
The role of periplasmic antioxidant enzymes (superoxide dismutase and thiol peroxidase) of the Shiga toxin‐producing Escherichia coli O157:H7 in the formation of biofilms
This study is the first mutational study to show the contribution of sodC and tpx gene products to the formation of an E. coli O157:H7 biofilm and suggests that these biofilms are physiologically heterogeneous and that oxidative stress defenses in both the exponential and stationary growth stages play important roles in theformation of STEC biofilm.
Cyclic stretching of soft substrates induces spreading and growth
It is suggested that the repeated pulling from a soft matrix can substitute for a stiff matrix in stimulating spreading, stress fibre formation and growth.
A gel-free 3D microfluidic cell culture system.
Bacterial metapopulations in nanofabricated landscapes
- J. Keymer, P. Galajda, C. Muldoon, Sungsu Park, R. Austin
- Environmental ScienceProceedings of the National Academy of Sciences
- 14 November 2006
By patterning habitat differences across the landscape, this device physically implements an adaptive landscape and observes rapid adaptation to large-scale, low-quality (high-stress) areas in landscapes with higher niche diversity.
Influence of topology on bacterial social interaction
- Sungsu Park, P. Wolanin, Robert Austin
- BiologyProceedings of the National Academy of Sciences…
- 17 November 2003
The results thus show that under nutrient-deprived conditions bacteria search out each other in a collective manner and that the bacteria can dynamically confine themselves to highly enclosed spaces.
Antipathogenic properties of green tea polyphenol epigallocatechin gallate at concentrations below the MIC against enterohemorrhagic Escherichia coli O157:H7.
The results suggest that EGCG at concentrations below itsMIC has significant antipathogenic effects against E. coli O157:H7.
Effect of bacteriocin produced by Lactococcus sp. HY 449 on skin-inflammatory bacteria.
Microfluidic gut-on-a-chip with three-dimensional villi structure
- Kyu-Young Shim, Dongwook Lee, Jeonghun Han, N. Nguyen, Sungsu Park, J. Sung
- BiologyBiomedical microdevices
- 27 April 2017
The results suggest that the combination of fluidic stimulus and 3D structure induces further improvement in gut functions, and provides insight into the effect of different tissue environment on gut cells.