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This paper considers the polyhedral structure of the precedence-constrained knapsack problem, which is a knapsack problem with precedence constraints imposed on the set of variables. The problem itself appears in many applications. Moreover, since the precedence constraints appear in many important integer programming problems, the polyhedral results can be(More)
The cDNAs encoding ethanol-inducible forms of rat and human cytochrome P-450s have been isolated, sequenced, and used to study the expression of this cytochrome P-450 during development and by various inducing agents. Polyclonal antibody against ethanol-inducible cytochrome P-450 was used to screen rat and human lambda gt11 cDNA expression libraries. The(More)
BACKGROUND Robot-assisted gastrectomy (RAG) has been developed in the hope of improving surgical quality and overcoming the limitations of conventional laparoscopically assisted gastrectomy (LAG) and open gastrectomy (OG) for gastric cancer. The aim of this study was to determine the extent of evidence in support of these ideals. METHODS A systematic(More)
OBJECTIVE To compare short-term surgical outcomes including financial cost of robotic and laparoscopic gastrectomy. BACKGROUND Despite a lack of supporting evidence, robotic surgery has been increasingly adopted as a minimally invasive modality for the treatment of gastric cancer because of its assumed technical superiority over conventional laparoscopy.(More)
We consider a cognitive radio network with an energy-harvesting secondary transmitter to improve both energy efficiency and spectral efficiency. The goal of this paper is to determine an optimal spectrum sensing policy that maximizes the expected total throughput subject to an energy causality constraint and a collision constraint. The energy causality(More)
Hybridomas were prepared from myeloma cells and spleen cells of BALB/c female mice immunized with hepatic cytochrome P-450E purified from the marine fish, Stenotomus chrysops (scup). Nine independent hybrid clones produced MAbs, either IgG1, IgG2b, or IgM, that bound to purified cytochrome P-450E in radioimmunoassay. Antibodies from one clone MAb (1-12-3),(More)
BACKGROUND Smith-Magenis syndrome (SMS) is a multiple congenital anomalies/mental retardation syndrome associated with a hemizygous deletion of chromosome 17, band p11.2. Characteristic features include neurobehavioural abnormalities such as aggressive and self-injurious behaviour and significant sleep disturbances. The majority of patients have a common(More)
BACKGROUND Moclobemide, an antidepressant with selective monoamine oxidase-A inhibitory action, is known to be metabolized by CYP2C19 and is also reported to be an inhibitor of CYP2C19, CYP2D6, and CYP1A2. To confirm the involvement of CYP2C19, we performed a pharmacokinetic interaction study. METHODS The effect of omeprazole on the pharmacokinetics of(More)
BACKGROUND Autosomal dominant optic atrophy (ADOA) is the commonest form of inherited optic neuropathy. Mutations in the OPA1 gene encoding a dynamin-related mitochondrial protein underlie ADOA and may perturb the biogenesis and maintenance of mitochondria. OBJECTIVE To investigate the mutation spectrum of the OPA1 gene and assess alterations in(More)
—We consider the routing and wavelength assignment (RWA) problem on WDM ring networks without wavelength conversion. When the physical network and required connections are given, RWA is the problem to select a suitable path and wavelength among the many possible choices for each connection such that no two paths using the same wavelength pass through the(More)