Learn More
PURPOSE To determine the efficacy of consolidation chemotherapy (CC) with docetaxel and cisplatin (DP) after concurrent chemoradiotherapy (CCRT) with the same agents in locally advanced non-small-cell lung cancer (LA-NSCLC). PATIENT AND METHODS Patients were randomly assigned to either CCRT alone (observation arm) or CCRT followed by CC (consolidation(More)
A phase II study was conducted to assess the efficacy and tolerability of capecitabine in combination with irinotecan (CAPIRI) in advanced colorectal cancer. Forty-seven patients with previously untreated metastatic or unresectable colorectal adenocarcinoma received capecitabine 1000 mg/m2 twice daily on days 2-15 and intravenous irinotecan 100 mg/m2 on(More)
OBJECTIVES The temporal relationship between simple renal cysts and incident hypertension is unknown. In this study, we assessed the time-dependent relationship between simple renal cysts and incident hypertension in a cohort of healthy middle-aged men. METHODS A cohort study was conducted with data for 4516 healthy men with no evidence of hypertension at(More)
BACKGROUND/AIMS As the population ages, endoscopic retrograde cholangiopancreaticography (ERCP) is being used increasingly as a diagnostic and therapeutic tool for elderly patients with pancreatobiliary disease. The aim of this study was to assess the outcomes, safety and complications associated with ERCP performed in the elderly patients. METHODS We(More)
OBJECTIVES Many chronic kidney disease (CKD) patients have persistent overt proteinuria despite angiotensin receptor blocker (ARB) treatment. This study investigated whether the initial difference in intrarenal renin-angiotensin system activity measured with urinary angiotensinogen would affect the antiproteinuric effects of ARB. METHODS Between September(More)
AIMS AND BACKGROUND For advanced cancers of the bile duct, gallbladder and ampulla of Vater, there are only a few treatment options. We explored the efficacy of the combination of gemcitabine, 5-fluorouracil and cisplatin for advanced biliary cancers. METHODS From September 2003 to April 2010, 28 patients with recurrent or metastatic biliary tract cancer(More)
BACKGROUND/AIMS An association between metabolic syndrome and impaired health-related quality of life (HRQoL) is still controversial. We investigated the association between metabolic syndrome in itself and HRQoL in the Korean adult population. METHODS The study is a cross-sectional analysis of 8,941 adults ≥19 years of age who participated in the 2007(More)
OBJECTIVE To investigate the development of nephrotoxicity associated with colistin dose, and whether this relationship differs depending on renal function. DESIGN A retrospective cohort study of patients who received intravenous colistin to treat infections caused by extensively drug-resistant Gram-negative microorganisms. Adult patients receiving(More)
Adiponectin plays an important role in the regulation of body weight, insulin sensitivity, lipid metabolism, and the inflammatory response. Adiponectin is elevated in hemodialysis patients. We investigated the association between altered serum adiponectin levels and the nutritional-inflammation status of hemodialysis patients. Forty-four hemodialysis(More)
OBJECTIVE To investigate the relationship between severity of peripheral polyneuropathy (PPN) and degree of depression and quality of life in chronic renal failure (CRF) patients on hemodialysis (HD). METHOD Forty seven chronic renal failure patients on hemodialysis were recruited (22 male, 25 female, mean age of 63.17±12.52) and etiology, disease(More)