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In previous studies we have demonstrated that the γ-aminobutryic acid-A (GABA-A) receptor antagonist oroxylin A has an awakening effect and it also represses ADHD-like behaviors (hyperactivity, impulsivity and inattention) in the spontaneously hypertensive rat (SHR) model of attention-deficit hyperactivity disorder (ADHD). We hypothesized that the effects(More)
In previous studies on 4-DOF parallel mechanisms with four sub-chains, only symmetric arrangement of those four chains connected to the top plate was considered. Such symmetric shape sometimes falls into a sort of architetural singularity. This work demonstrates that an asymmetric placement of the four chains on the top platform is desired to minimize the(More)
Two parallel mechanisms, a 1T2R (one translational motion and 2-DOF rotational motions) and a 1T3R (one translational motion and 3-DOF spherical motion), are proposed. The 1T2R mechanism consists of three sub chains. Specifically, the middle sub chain has a similar joint arrangement with a PRR serial mechanism. Two revolute joints located at the top plate(More)
The development of cardiac CT has provided a non-invasive alternative to echocardiography, exercise electrocardiogram, and invasive angiography and cardiac CT continues to develop at an exponential speed even now. The appropriate use of cardiac CT may lead to improvements in the medical performances of physicians and can reduce medical costs which(More)
BACKGROUND Microvascular angina (MVA) is characterized by anginal chest pain, an abnormal stress test, and normal coronary arteries on coronary angiography. Although the exact pathogenesis remains unclear, endothelial dysfunction is a contributing factor. To date, there exists no specific therapy for this disease. Phosphodiesterase-5 inhibitor improves the(More)
This work presents the kinematic modeling and motion planning algorithm for an omni-directional mobile robot with kinematic redundancy. This robot consists of three wheel mechanisms each of which has one redundant joint as compared to the operational degrees. Initially, the kinematic modeling of this robot is conducted. Next, using such a kinematic(More)
Less degree-of-freedom robots are useful for special applications. Specifically, practical application of 4-DOF parallel mechanism has been rare, though synthesis on this type has been conducted quite a few. Recently, we proposed a revolute joint-based 3T1R 4-DOF parallel mechanism having Schonflies motions whose output rotational motion is a roll motion.(More)
Breast metastasis from nonmammary malignant neoplasms is uncommon, and it accounts for approximately 2% of all breast tumors. Distant metastasis of thymoma is very rare, and especially to extrathorcic areas. We report a female who had a metastatic thymoma in her breast 20 years after undergoing resection for a non-invasive thymoma. She presented with a(More)
We report here on a neonate with congenital cerebellar mixed germ cell tumor, and this initially presented as cerebellar hemorrhage. Postnatal cranial ultrasonography revealed an echogenic cerebellar mass that exhibited the signal characteristics of hemorrhage rather than tumor on MR images. The short-term follow-up images also suggested a resolving(More)
OBJECTIVE This study assessed the outcomes of using vascular closure devices following percutaneous transfemoral endovascular procedures in the patients who were treated with heparin, abciximab or thrombolytics (urokinase or t-PA) during the procedures. MATERIALS AND METHODS From March 28, 2003 to August 31, 2004, we conducted a prospective and randomized(More)