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The synthesis of polyunsaturated fatty acids (PUFAs), the most abundant fatty acids in plants, begins with a reaction catalyzed by fatty acid desaturase 2 (FAD2; EC, also called microsomal oleate Δ12-desaturase. Since the FAD2 gene was first identified in Arabidopsis thaliana, FAD2 research has gained wide interest as the essential enzyme for(More)
Background. The decline of Helicobacter pylori (H. pylori) eradication rates with standard triple therapy resulted in a search for novel therapies for first-line therapy of H. pylori infection. Aim. The aim of the study is to compare the efficacy of concomitant therapy with sequential therapy as the first-line therapy of H. pylori eradication. Methods. We(More)
Wegener's granulomatosis (WG) is an inf lammatory disorder of presumed autoimmune pathogenetic mechanism characterized by granulomatous in-f lammation of the respiratory tract, necrotizing vasculitis, and glomeru-lonephritis. However, the disease can affect any organ and shows diverse clinical manifestations. Although an-tineutrophil cytoplasmic antibodies(More)
Henoch-Schönlein purpura secondary to infective endocarditis in a patient with pulmonary valve stenosis and a ventricular septal defect Henoch-Schönlein purpura (HSP) is a systemic, small-vessel vasculitic syndrome characterized by palpable purpura, arthralgia, abdominal pain, and renal disease. The underlying pathogenesis of HSP remains unclear.(More)
PURPOSE Optimal management of colonoscopic perforation (CP) is controversial because early diagnosis and prompt management play critical roles in morbidity and mortality. Herein, we evaluate the outcomes and clinical characteristics of patients with CP according to treatment modality to help establish guidelines for managing CP. METHODS Our retrospective(More)
AIM To identify prognostic factors and to correlate APC mutations with clinical features, including extracolic manifestations. METHODS One hundred thirty-five patients who underwent surgical procedures for familial adenomatous polyposis (FAP) were included. FAP was diagnosed when the number of adenomatous polyps was > 100. Data related to patient,(More)
OBJECTIVE In hypertensive patients with proteinuria, renin-angiotensin system (RAS) blockade would be beneficial for controlling both blood pressure and proteinuria. We aimed to evaluate prescription pattern of RAS blockade in Korean hypertensive patients with proteinuria. DESIGN AND METHOD We used the National Health Insurance Service-National Sample(More)
BACKGROUND Dementia is common in end-stage renal disease (ESRD) patients on hemodialysis (HD) and is associated with worse outcomes. This study aimed to investigate the risk of major adverse cardiac and cerebrovascular event (MACCE) in elderly patients with dementia initiating HD. METHODS Using the database from the Health Insurance Review & Assessment(More)
Pneumatosis cystoides intestinalis (PCI) is a rare condition characterized by multiple gas-filled cysts of varying size in the wall of gastrointestinal tract. PCI may idiopathic or secondary to various disorders. The etiology and pathogenesis of PCI are unclear. Treatment is usually conservative, and includes oxygen and antibiotics therapy. Surgery is(More)