Background. The decline of Helicobacter pylori (H. pylori) eradication rates with standard triple therapy resulted in a search for novel therapies for first-line therapy of H. pylori infection. Aim. The aim of the study is to compare the efficacy of concomitant therapy with sequential therapy as the first-line therapy of H. pylori eradication. Methods. We… (More)
PURPOSE Optimal management of colonoscopic perforation (CP) is controversial because early diagnosis and prompt management play critical roles in morbidity and mortality. Herein, we evaluate the outcomes and clinical characteristics of patients with CP according to treatment modality to help establish guidelines for managing CP. METHODS Our retrospective… (More)
Good oncologic outcomes, demonstrated by a complete pathologic response after preoperative chemoradiotherapy (PCRT), have led to local excision (LE) in selected patients with rectal cancer. We evaluated the oncologic safety of LE compared with total mesorectal excision (TME) in patients with ypT0-T1 rectal cancer.A retrospective review of 304 patients who… (More)
Henoch-Schönlein purpura secondary to infective endocarditis in a patient with pulmonary valve stenosis and a ventricular septal defect Henoch-Schönlein purpura (HSP) is a systemic, small-vessel vasculitic syndrome characterized by palpable purpura, arthralgia, abdominal pain, and renal disease. The underlying pathogenesis of HSP remains unclear.… (More)
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Wegener's granulomatosis (WG) is an inf lammatory disorder of presumed autoimmune pathogenetic mechanism characterized by granulomatous in-f lammation of the respiratory tract, necrotizing vasculitis, and glomeru-lonephritis. However, the disease can affect any organ and shows diverse clinical manifestations. Although an-tineutrophil cytoplasmic antibodies… (More)
Sjögren's syndrome is a chronic autoimmune disorder characterized by lymphocytic infiltration of the lacrimal and salivary glands, leading to dryness of eyes (kerato-conjunctivitis sicca) and mouth (xerostomia). The skin lesions in Sjögren's syndrome are usually manifested as xeroderma, but sometimes appear as annular erythema or vasculitis. Central nervous… (More)