Sung I. Hong

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Kisspeptin and its receptor, GPR54, play a pivotal role in vertebrate reproduction. Recent advances in bioinformatic tools combined with comparative genomics have led to the identification of a large number of kisspeptin and GPR54 genes in a variety of vertebrate species. Genome duplications may have produced at least two isoforms of both ligand (KiSS1 and(More)
ÐMemory bandwidth is rapidly becoming the limiting performance factor for many applications, particularly for streaming computations such as scientific vector processing or multimedia (de)compression. Although these computations lack the temporal locality of reference that makes traditional caching schemes effective, they have predictable access patterns.(More)
Processor speeds are increasing rapidly, and memory speeds are not keeping up. Streaming computations (such as multi-media or scientific applications) are among those whose performance is most limited by the memory bottleneck. Rambus hopes to bridge the processor/memory performance gap with a recently introduced DRAM that can deliver up to 1.6Gbytes/sec. We(More)
Gonadotropin-releasing hormone (GnRH) and the GnRH receptor (GnRHR) play an important role in vertebrate reproduction. Although many GnRHR genes have been identified in a large variety of vertebrate species, the evolutionary history of GnRHR in vertebrates is unclear. To trace the evolutionary origin of GnRHR we examined the conserved synteny of chromosomes(More)
We previously reported that oroxylin A, a γ-aminobutyric acid A (GABAA) receptor antagonist, ameliorates drugs-induced memory impairments. We synthesized several oroxylin A derivatives in efforts to find a substance that has pro-cognitive effects as well as improves sensorimotor gating. The aim of the present study is to investigate the effect of a novel(More)
Epilepsy is a complex neurological disorder characterized by the repeated occurrence of electrical activity known as seizures. This activity induces increased intracellular calcium, which ultimately leads to neuronal damage. Houttuyniae Herba, the aerial part of Houttuynia cordata, has various pharmacological effects and is widely used as a traditional(More)
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