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Vir-Mir db: prediction of viral microRNA candidate hairpins
TLDR
An interface for users to query the predicted viral miRNA hairpins based on taxonomic classification, and a host target gene prediction service based on the RNAhybrid program and the 3′-UTR gene sequences of human, mouse, rat, zebrafish, rice and Arabidopsis are established. Expand
Aberrant hypermethylation of miR-9 genes in gastric cancer
TLDR
Methylation-mediated silencing of these three miR-9 genes can be reactivated in gastric cancer cells through 5-Aza-dC treatment and showed that it was significantly down-regulated in Gastric cancers compared with adjacent normal tissues. Expand
Epigenetic regulation of miR‐34b and miR‐129 expression in gastric cancer
TLDR
It is shown that tumor‐specific methylation silences miR‐34b andmiR‐129 in gastric cancer cells, and the methylation status correlated inversely with their expression patterns. Expand
The Silkworm (Bombyx mori) microRNAs and Their Expressions in Multiple Developmental Stages
TLDR
The results indicated that miRNAs may play key regulatory roles in specific developmental stages in the silkworm, such as ecdysis, as well as comparative analyses with other sequenced insect species. Expand
Intronic microRNA: discovery and biological implications.
TLDR
A modified scanning pipeline is used using criteria based on the features of known pre-miRNAs and phylogenetic conservation for predicting intronic miRNAs to propose hypothetical models of such feedback regulation on host protein-coding genes by selecting the transcription factors as miRNA targets or by protein-protein interactions between intronics miRNA host gene product and miRNA target gene products. Expand
The effects of storage temperature and duration of blood samples on DNA and RNA qualities
TLDR
The effects of storage temperature and storage duration of whole blood on DNA and RNA qualities and DNA methylation status are investigated to provide a reference for dealing with blood samples. Expand
Discovery and characterization of medaka miRNA genes by next generation sequencing platform
TLDR
It is concluded that the evolutionally conserved miRNAs were usually the most abundant ones in medaka, and identifying and characterizing medaka miRNA genes would benefit the studies using medaka as a model organism. Expand
miRNA arm selection and isomiR distribution in gastric cancer
TLDR
In-depth analyses to examine the arm selection and isomiRs using NGS platform showed the 5p arm and 3p arm miRNA derived from the same pre-miRNAs have different tissue expression preference, one preferred normal tissue and the other preferred tumor tissue, which strongly implied that there could be other mechanism controlling mature miRNA selection in addition to the known hydrogen-bonding selection rule. Expand
Epigenetic regulation of miR‐196b expression in gastric cancer
TLDR
This work uses a sequential methylation analysis to reveal that the methylation status correlated well with miR‐196b expression in different cell lines and demonstrates that abnormal DNA hypomethylation induces overexpression of miR-196b in gastric cancer. Expand
Aberrant expression of miR‐196a in gastric cancers and correlation with recurrence
TLDR
It is demonstrated that miR •196a exerts an oncogenic role in gastric cancer and miR‐196a may be a novel biomarker for detecting gastriccancer and for monitoring disease recurrence. Expand
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