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BACKGROUND This study was performed to determine the feasibility and safety of salvage chemotherapy, using docetaxel and cisplatin in 5-fluorouracil (5-FU) and cisplatin-pretreated esophageal cancer. METHODS Patients with metastatic or recurrent esophageal squamous cell carcinoma that had previously been treated with 5-FU and cisplatin chemotherapy or(More)
BACKGROUND/AIMS There are controversies on the efficacy and safety of endoscopic submucosal dissection (ESD) for un-differentiated early gastric cancer (EGC) despite the expansion of ESD indications. The aim of this study was to evaluate the long term outcome of ESD compared to that of surgical treatment in patients with undifferentiated EGC. METHODS A(More)
BACKGROUND Endoscopic retrograde biliary drainage (ERBD) by using a plastic stent is suggested to be as effective as endoscopic nasobiliary drainage (ENBD) for temporary biliary drainage in acute suppurative cholangitis (ASC). However, there are few studies that compared ERBD and ENBD in ASC. OBJECTIVES We compared the safety and efficacy of ERBD and ENBD(More)
BACKGROUND Previous differential coexpression analyses focused on identification of differentially coexpressed gene pairs, revealing many insightful biological hypotheses. However, this method could not detect coexpression relationships between pairs of gene sets. Considering the success of many set-wise analysis methods for microarray data, a coexpression(More)
BACKGROUND We aimed to investigate the efficacy of computer-aided detection (CAD) for MRI in the assessment of tumor extent, lymph node status, and multifocality in invasive breast cancers in comparison with other breast imaging modalities. METHODS Two radiologists measured the maximum tumor size, as well as, analyzed lymph node status and multifocality(More)
We propose a novel method, called heterogeneous clustering ensemble (HCE), to generate robust clustering results that combine multiple partitions (clusters) derived from various clustering algorithms. The proposed method combines partitions of various clustering algorithms by means of newly-proposed the selection and the crossover operation of the genetic(More)
BACKGROUND/AIMS Although triple combination therapy containing a proton pump inhibitor (PPI) and two antibiotics is considered as a standard regimen for the first-line anti-Helicobacter pylori treatment, the recent trend of eradication rates following this therapy has been declined in the last few years. The purpose of this study was to investigate the(More)
In modern data mining applications, clustering algorithms are among the most important approaches, because these algorithms group elements in a dataset according to their similarities, and they do not require any class label information. In recent years, various methods for ensemble selection and clustering result combinations have been designed to optimize(More)
BACKGROUND/AIMS Food residue is frequently observed in the gastric remnant after distal gastrectomy, despite adequate preparation. We devised a water-intake method to reduce food residue in the gastric remnant by drinking large quantities of water in a short time. The aims of this study were to identify the risk factors for food residue and to study the(More)
BACKGROUND/AIMS Epigallocatechin-3-gallate (EGCG), the primary catechin in green tea, has anti-inflammatory and anti-oxidative properties. The aim of the current study was to characterize the impact of EGCG on lipopolysaccharide (LPS)-induced innate signaling in bone marrow-derived macrophages (BMMs) isolated from ICR mice. METHODS The effect of EGCG on(More)