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This review summarizes the evidence that apoptosis is modulated by intracellular excess or deficiency of Zn 2+ , considers mechanisms whereby Zn 2+ may influence apoptosis, and delineates gaps in(More)
R ecent advances in m etal carcinogenesis are com prehensively re ­ viewed, including (a) epidemiological and clinical aspects, (b) carcinogen­ esis bioassays, (c) bacterial mutagenesis, (d)(More)
The carcinogenic effects of metals in man and experimental animals are summarized. Attention is focused primarily on (a) four metals (As, Cd, Cr, and Ni) that have been implicated as human(More)