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- Hoseok Song, Sun-Ku Chung, Yang Xu
- Cell stem cell
- 2010
Although mouse models have been valuable for studying human disease, the cellular and physiological differences between mouse and human have made it increasingly important to develop more relevant… (More)
- Sun-Ku Chung, Joo-Young Kim, In-Beom Kim, Sang-Ick Park, Kyung-Hee Paek, Jae-Hwan Nam
- Virology
- 2005
Coxsackievirus B3 (CVB3) is nonenveloped and has a single-stranded positive-sense RNA genome. CVB3 induces myocarditis and ultimately dilated cardiomyopathy. Although there are mounting evidences of… (More)
- Bu-Yeo Kim, Sangkyun Jeong, +5 authors Sun-Ku Chung
- Experimental & molecular medicine
- 2016
Fibrodysplasia ossificans progressiva (FOP) syndrome is caused by mutation of the gene ACVR1, encoding a constitutive active bone morphogenetic protein type I receptor (also called ALK2) to induce… (More)
- Joo-Young Kim, Eun-Seok Jeon, +6 authors Jae-Hwan Nam
- Vaccine
- 2005
Coxsackievirus (CVB) 3 induces viral myocarditis and ultimately dilated cardiomyopathy (DCM). However, there is no vaccine in clinical use. We constructed recombinant CVB3 plasmids using a highly… (More)
- Ha Young Hwang, Joo-Young Kim, Joong-Yeon Lim, Sun-Ku Chung, Jae-Hwan Nam, Sang Ick Park
- Virus research
- 2007
Activating transcription factor 3 (ATF3) is an early-induced gene involved in diverse cellular functions in response to various stresses including viral infection. Here we observed marked reduction… (More)
- Sun-Ku Chung, Hyunjoo Yu, Ah Yeon Park, Jong Yeol Kim, Seongwon Cha
- BMC Complementary and Alternative Medicine
- 2014
BackgroundAbnormal lipid concentrations are risk factors for atherosclerosis and cardiovascular disease. The pathological susceptibility to cardiovascular disease risks such as metabolic syndrome,… (More)
- Joo-Young Kim, Sun-Ku Chung, +4 authors Sang Ick Park
- Virus research
- 2007
Chemically synthesized small interfering RNA (siRNA) has been used as an anti-coxsackievirus B3 (CVB3) agent. Herein, we investigated whether vector-derived short hairpin RNAs (shRNA) targeting CVB3… (More)
- Seo-young Lee, Sun-Ku Chung
- Stem cells international
- 2016
The recent advent of induced pluripotent stem cells (iPSCs) and gene therapy tools has raised the possibility of autologous cell therapy for rare genetic diseases. However, cellular reprogramming is… (More)
- Soo A. Oh, Inchul Yang, Yoonsoo Hahn, Yong-Kook Kang, Sun-Ku Chung, Sangkyun Jeong
- Scientific reports
- 2015
Despite the recent technological advances in DNA quantitation by sequencing, accurate delineation of the quantitative relationship among different DNA sequences is yet to be elaborated due to… (More)
- Sun-Ku Chung, Shengyun Zhu, Yang Xu, Xuemei Fu
- Protein & Cell
- 2014
As a critical tumor suppressor, p53 is inactivated in human cancer cells by somatic gene mutation or disruption of pathways required for its activation. Therefore, it is critical to elucidate the… (More)