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  • Joyce A. Wilson, Sumedha D Jayasena, +7 authors Christopher D. Richardson
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2003 (First Publication: 19 February 2003)
  • RNA interference represents an exciting new technology that could have therapeutic applications for the treatment of viral infections. Hepatitis C virus (HCV) is a major cause of chronic liverExpand
  • Vanvimon Saksmerprome, Manami Roychowdhury-Saha, Sumedha D Jayasena, Anastasia Khvorova, Donald H Burke
  • Biology, Medicine
  • RNA
  • 2004 (First Publication: 1 December 2004)
  • Tertiary stabilizing motifs (TSMs) between terminal loops or internal bulges facilitate folding of natural hammerhead ribozymes (hRz) under physiological conditions. However, both substrate andExpand