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Endothelial cell activation in patients with decompensated heart failure.

• Paolo C Colombo, Javier E Banchs, +9 authors Thierry H LeJemtel
• Circulation
• 2005

BACKGROUND Vascular endothelial functions, other than nitric oxide (NO)-mediated control of vasomotor tone, are poorly characterized in patients with chronic heart failure (CHF). Veins and arteries are exposed to the same circulating proinflammatory mediators in patients with CHF. The present study tested whether endothelial cell activation occurs in veins… (More)

Biopsy coupled to quantitative immunofluorescence: a new method to study the human vascular endothelium.

• Paolo C Colombo, Anthony W Ashton, +8 authors Thierry H Le Jemtel
• Journal of applied physiology
• 2002

Limited availability of endothelial tissue is a major constraint when investigating the cellular mechanisms of endothelial dysfunction in patients with metabolic and cardiovascular diseases. We propose a novel approach that combines collection of 200-1,000 endothelial cells from a superficial forearm vein or the radial artery, with reliable measurements of… (More)

Association between off-label use of drug-eluting stents and subsequent stent thrombosis: a case-control analysis.

• Asaf Rabinovitz, Dara M Bier, +7 authors V S Srinivas
• The Journal of invasive cardiology
• 2010

OBJECTIVES We sought to examine the association between off-label drug-eluting stent (DES) use and stent thrombosis (ST) in unselected patients undergoing percutaneous coronary intervention (PCI). BACKGROUND DES are frequently used in clinical and angiographic scenarios not initially tested and approved by the FDA (off-label use) resulting in lingering… (More)

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