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  • Tiffany N Mackenzie, Nameeta Mujumdar, +5 authors Ashok Kumar Saluja
  • Medicine, Biology
  • Molecular Cancer Therapeutics
  • 2013 (First Publication: 1 May 2013)
  • Pancreatic ductal adenocarcinoma (PDAC), one of the deadliest malignancies, is resistant to current chemotherapies. We previously showed that triptolide inhibits PDAC cell growth in vitro and blocksExpand
  • Sulagna Banerjee, Veena Sangwan, +4 authors Ashok Kumar Saluja
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2013 (First Publication: 15 October 2013)
  • Background: Preclinical evaluation of triptolide shows pancreatic tumor regression in animal models. Results: Triptolide deregulates glycosylation of Sp1, leading to its decreased activity andExpand
  • Tara C K Krosch, Veena Sangwan, +4 authors Selwyn Vickers
  • Medicine
  • American journal of surgery
  • 2013 (First Publication: 1 April 2013)
  • BACKGROUND Neuroblastoma is an aggressive pediatric malignancy with significant chemotherapeutic resistance. We assessed triptolide as a potential therapy. METHODS SH-SY5Y and IMR-32 neuroblastomaExpand