Sukru Sindel

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OBJECTIVES To determine the significance of a newly described marker of inflammation procalcitonin (PCT), and to investigate its relationship to conventional markers of inflammation, such as C-reactive protein (CRP), fibrinogen, and erythrocyte sedimentation rate (ESR), in patients on peritoneal dialysis (PD) and with peritonitis. DESIGN A prospective,(More)
UNLABELLED Quality of life (QOL) has recently been explored as one of the main outcomes of renal replacement therapy. In this study, we sought to compare three groups of patients-hemodialysis, peritoneal dialysis, and transplantation-with regard to QOL. METHODS Seventy-five hemodialysis, 41 peritoneal dialysis and 20 transplant patients were given Patient(More)
This population-based epidemiological study was aimed to evaluate the daily salt intake and its relation to blood pressure in a representative group of Turkish population. The enrolled normotensive and hypertensive individuals (n = 1970) completed a questionnaire including demographics, dietary habits, hypertension awareness and drug usage. Blood pressure(More)
Chronic allograft dysfunction (CAD) is the most common cause of allograft failure in the long-term, and current immunologic strategies have little effect on this condition. The renin-angiotensin system (RAS) plays important roles progression of chronic renal disease. It is thought that plasminogen activator inhibitor-1 (PAI-1) functions in the RAS, in(More)
The protective effect of N-acetylcysteine (NAC) on nephrotoxicity due to contrast nephropathy and reperfusion-induced ischemia has been reported in experimental models. However, its efficacy on colistin-induced nephrotoxicity has not been elucidated yet. The primary aim of this study was to evaluate the nephrotoxic effect of colistin and to investigate the(More)
INTRODUCTION The association between hyperuricemia and cardiovascular disease in hypertensive subjects is controversial. Attempts to elucidate the possible association between hyperuricemia and early atherosclerosis in hypertensive patients may provide alternative prevention or therapy targets for future cardiovascular events. METHODS A total of 67(More)
It has been shown that beta-glucan (BG), which has antioxidant and immunomodulatory effects, attenuats renal ischemia–reperfusion injury. We aimed to investigate whether BG might have a preventive role against the development of contrast-induced nephropathy and to compare its effect with nebivolol (Nb) and N-acetylcysteine (NAC). Thirty-six Wistar albino(More)
Angiotensin II (A II) when given through the renal artery of the rabbit isolated perfused kidney elicited a concentration-dependent increase in perfusion pressure (PP) and urine flow (UF). Noradrenaline (NA) produced similar effect in PP but slightly not significantly increased UF. Addition of UK 38,485, a thromboxane A2 (TXA2)-synthetase inhibitor, to the(More)
Cyclosporine-A is a highly potent immunosuppressive agent for solid organ transplantation, but has many side effects including nephrotoxicity, hypertension, gum hyperplasia, hepatotoxicity, and neurotoxicity. Neurotoxicity is a less known toxic effect. The pathogenesis of this effect is unclear. However, it has been postulated that hypomagnesemia,(More)