Sukhpal Singh Sandhu

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PURPOSE To determine the association of genetic variants of the VEGFA gene with outcome of anti-vascular endothelial growth factor (VEGF) treatment in neovascular age-related macular degeneration (AMD). DESIGN A prospective cohort study. PARTICIPANTS We included 201 consecutive patients receiving anti-VEGF injections for neovascular AMD. METHODS(More)
AIMS To assess the diagnostic accuracy of optical coherence tomography (OCT), with/without colour fundus photographs, in predicting fundus fluorescein angiography (FFA) findings in patients suspected of having choroidal neovascularisation (CNV). METHODS A consecutive series of patients suspected of having CNV underwent OCT and stereo FFA images, which(More)
OBJECTIVES Cranial CT scans are amongst the most frequently performed radiological investigations performed in most developed countries. However, these tests are relatively expensive and economic realities should compel physicians to re-evaluate the utilization of this technology. The aim of this study was to review the utilization pattern and effect on(More)
BACKGROUND/AIMS To evaluate retrospectively the clinical outcomes of patients presenting with submacular hemorrhage (SMH) secondary to neovascular age-related macular degeneration (nAMD), treated by vitrectomy, submacular tissue plasminogen activator (tPA) injection and pneumatic displacement of SMH with air followed by postoperative intravitreal(More)
Although acute optic neuropathy has been rarely reported in patients with Behçet's disease, a detailed description of its clinical course is lacking. We report in detail the course of acute optic neuropathy in two patients with Behçet's disease. Our experience suggests that it can be bilateral, can affect both eyes simultaneously, and can be recurrent. The(More)
The exact incidence of submacular haemorrhage (SMH) in patients with neovascular age-related macular degeneration (nAMD) is unknown, and risk factors for its occurrence ill defined. It is known, however, to be a relatively common problem and important because the visual prognosis of these patients is poor. Unfortunately, patients with significant SMH were(More)
OBJECTIVE To assess if posterior juxtascleral application of 40 mg triamcinolone acetonide (TA), given at the same time as initial photodynamic therapy (PDT) for predominantly classic choroidal neovascularization (CNV) related to age-related macular degeneration affects lesion growth at 3 and 6 months. DESIGN Comparative (nonrandomized) interventional(More)
BACKGROUND Careful surgical management of traumatic wounds is important in open globe injury repair. This study examines the clinical outcomes following repair of open globe injuries with particular focus on wound-related issues. DESIGN Retrospective, cohort study of consecutive open globe injuries presenting to a tertiary referral eye hospital from 1(More)