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Good pain control after surgery is important to prevent negative outcomes such as tachycardia, hypertension, myocardial ischemia, decrease in alveolar ventilation, and poor wound healing. Exacerbations of acute pain can lead to neural sensitization and release of mediators both peripherally and centrally. Clinical wind up occurs from the processes of(More)
BACKGROUND It is established that opioid receptors are present in the dorsal root ganglia and the central as well as peripheral terminals ofprimary afferent neurons. Now, it has been shown that peripheral terminals of afferent nerves can be the sites of the intrinsic modulation of nociception and that opioid analgesia can be mediated by peripheral opioid(More)
The aim of the Forum for Information Retrieval Evaluation (FIRE) is to create a Cranfield-like evaluation framework in the spirit of TREC, CLEF and NTCIR, for Indian Language Information Retrieval. For the first year, six Indian languages have been selected: Bengali, Hindi, Marathi, Punjabi, Tamil, and Telugu. This poster describes the tasks as well as the(More)
BACKGROUND Opioid-induced hyperalgesia (OIH) refers to a phenomenon whereby opioid administration results in a lowering of pain threshold, clinically manifest as apparent opioid tolerance, worsening pain despite accelerating opioid doses, and abnormal pain symptoms such as allodynia. AIM The current review, while providing a clinically oriented updated(More)
PAIN is “an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.” In settings where pain is poorly controlled, patients suffer needlessly and may develop untoward emotional and cognitive responses that negatively affect behavior, rehabilitation, and quality of life. Providing(More)
SUMMARY The administration of intravenous fluids is one of the most common and universal interventions in medicine. Colloids are an alternative to the frequently used crystalloids, with highly variable use depending on a myriad of clinical variables. A colloid is defined as a high molecular weight (MW) substance that largely remains in the intravascular(More)
Inadequately treated acute pain is a global healthcare problem that causes significant patient suffering and disability, risk of chronicity, increased resource utilization, and escalating healthcare costs. Compounding the problem is the lack of adequate instruction in acute pain management available in medical schools worldwide. Incorporating acute pain(More)
Pain relief after laparoscopic cholecystectomy (LC) is an issue of great practical importance. Pain after LC has several origins: incisional, local visceral, peritoneal, and referred. Several modalities have been employed for achieving effective and safe analgesia: nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase-2 (COX-2) inhibitors,(More)
Pain from surgical procedures occurs as a consequence of tissue trauma and may result in physical, cognitive, and emotional discomfort. Almost a century ago, researchers first described a possible relationship between intraoperative tissue damage and an intensification of acute pain and long-term postoperative pain, now referred to as central sensitization.(More)
BACKGROUND Robotic-assisted surgery has evolved over the past 2 decades with constantly improving technology that assists surgeons in multiple subspecialty disciplines. The surgical requirements of lithotomy and steep Trendelenburg positions, along with the creation of a pneumoperitoneum and lack of direct access to the patient all present management(More)