Suk-Tak Chan

Learn More
Amblyopia, sometimes called "lazy eye," is a relatively common developmental visual disorder well characterized behaviorally; however, the neural substrates associated with amblyopia in humans remain unclear. We hypothesized that abnormalities in the cerebral cortex of subjects with amblyopia exist, possibly as a result of experience-dependent neuronal(More)
Cerebral deficit has been implicated in the genesis of strabismus and in the mechanisms adopted to compensate for the visual disorder. Voxel-based morphometry (VBM) was applied to magnetic resonance images of strabismic adults to detect any abnormal brain anatomy, which could not be easily identified by simple inspection. The gray matter volume in(More)
PURPOSE Pulsatile ocular blood flow (POBF) assessment measures the choroidal circulation and provides diagnostic value to certain ocular diseases such as glaucoma. This technique assumes a constant ocular rigidity and is influenced by axial length, diurnal variation, and age. This study investigated the effect of age on POBF, with consideration of the above(More)
Functional and spatial hierarchical organization of increasingly language-like word forms has been proposed for alphabetic languages at the occipitotemporal cortex for visual word recognition. In the logographic Chinese language system, similar functional and spatial hierarchical presentations of brain responses to sublexical orthographic structure are(More)
Previous work has shown that acupuncture stimulation evokes deactivation of a limbic-paralimbic-neocortical network (LPNN) as well as activation of somatosensory brain regions. This study explores the activity and functional connectivity of these regions during acupuncture vs. tactile stimulation and vs. acupuncture associated with inadvertent sharp pain.(More)
BACKGROUND Pulsatile ocular blood flow (POBF) assessment measures the choroidal circulation and therefore provides data with diagnostic value in certain ocular diseases, such as glaucoma. The technique assumes a constant pressure-volume relationship. The current study investigated the effect of axial length on POBF from subjects with axial anisometropia.(More)
Previous work from our team and others has shown that manual acupuncture at LI4 (hegu), ST36 (zusanli), and LV3 (taichong) deactivates a limbic-paralimbic-neocortical brain network, and at the same time activates somatosensory regions of the brain. The objective of the present study was to explore the specificity and commonality of the brain response to(More)
cytokines. (2) The anti-inflammatory properties of NSAIDs block the oxytocin receptors in the trigeminal system. Without the interference of NSAIDs, intranasal oxytocin reduced pain in 42 % of chronic migraine patients at 2 h and 55 % at 4 h, compared to 11 and 28 % for placebo. Migraine is one of the major symptoms of fibromyalgia. So Yeomans’ presentation(More)
BACKGROUND CONTEXT Multifidus cross-sectional area was often measured in chronic low back pain (LBP) patients to estimate the muscle activity for spinal stability. However, such estimation may be inadequate as the contribution of muscle elasticity in muscle activity is ignored. In vivo quantitative data on multifidus elasticity is therefore important for(More)
A BCI-FES training platform has been designed for rehabilitation on chronic stroke patients to train their upper limb motor functions. The conventional functional electrical stimulation (FES) was driven by userspsila intention through EEG signals to move their wrist and hand. Such active participation was expected to be important for motor rehabilitation(More)