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Osteopontin splice variants differentially modulate the migratory activity of hepatocellular carcinoma cell lines.
- S. Chae, Hyoung-Oh Jun, +6 authors K. Kim
- Biology, Medicine
- International journal of oncology
- 1 December 2009
Osteopontin (OPN, SPP1) is a secretory extracellular matrix protein that has been implicated in cancer-associated mechanisms such as metastasis, invasion and angiogenesis. Three OPN isoforms (OPN-a,… Expand
Disruption of Ninjurin1 Leads to Repetitive and Anxiety-Like Behaviors in Mice
- Hoang Le, Bum Ju Ahn, +16 authors Kyuwon Kim
- Psychology, Medicine
- Molecular Neurobiology
- 1 November 2017
Over the last few decades, molecular neurobiology has uncovered many genes whose deficiency in mice results in behavioral traits associated with human neuropsychiatric disorders such as autism,… Expand
Betaine Promotes LKB1-AMPK Activation Inhibits UVB-Mediated Senescence of Human Epidermal Keratinocytes Through Autophagy Induction
Betaine demonstrations antioxidative activity, enhances organic osmolytic activity and is an important cofactor in methylation. However, the main mechanisms betaine-induced autophagy in human dermal… Expand