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Osteopontin splice variants differentially modulate the migratory activity of hepatocellular carcinoma cell lines.
Osteopontin (OPN, SPP1) is a secretory extracellular matrix protein that has been implicated in cancer-associated mechanisms such as metastasis, invasion and angiogenesis. Three OPN isoforms (OPN-a,Expand
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Disruption of Ninjurin1 Leads to Repetitive and Anxiety-Like Behaviors in Mice
Over the last few decades, molecular neurobiology has uncovered many genes whose deficiency in mice results in behavioral traits associated with human neuropsychiatric disorders such as autism,Expand
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Betaine Promotes LKB1-AMPK Activation Inhibits UVB-Mediated Senescence of Human Epidermal Keratinocytes Through Autophagy Induction
Betaine demonstrations antioxidative activity, enhances organic osmolytic activity and is an important cofactor in methylation. However, the main mechanisms betaine-induced autophagy in human dermalExpand