Suhaib Ahmed

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BACKGROUND We have investigated a strategy for identifying and counseling carriers of recessively inherited disorders in developing countries where consanguineous marriage is common. In such communities, gene variants are trapped within extended families, so that an affected child is a marker of a group at high genetic risk. METHODS Fifteen large(More)
CD5-positive B-ALL is a rare variant of Acute Lymphoblastic Leukemia (ALL). In literature, only three cases have been reported so far. This fourth case report describes a young lady who was diagnosed as ALL (L-2) on bone marrow examination and was found to be CD5 positive B-cell acute lymphoblastic leukemia on immunophenotyping. Cytogenetic analysis(More)
OBJECTIVE To determine the frequency of factor V leiden mutation. DESIGN Observational study. PLACE AND DURATION OF STUDY One-year, January 2001 to December 2001 at the Armed Forces Institute of Pathology, Rawalpindi, Pakistan. PATIENTS AND METHODS Two hundred subjects each of apparently healthy and unrelated Punjabi and Pathan origins were included(More)
OBJECTIVE To determine the association of Helicobacter pylori infection in patients presenting with idiopathic thrombocytopenic purpura (ITP). METHODS From March 2007 to March 2008, thirty adult patients with ITP and 30 age and sex matched healthy controls were investigated for the presence of H. pylori infection by Helicobacter pylori stool antigen(More)
OBJECTIVE To determine the frequency of Janus associated kinase 2 ( JAK2) mutation in patients of polycythemia vera (PV). STUDY DESIGN Descriptive cross-sectional. PLACE AND DURATION OF STUDY Haematology Department, Armed Forces Institute of Pathology (AFIP), Rawalpindi, from January 2008 to December 2009. METHODOLOGY Forty-six consecutive patients of(More)
The XmnI Ggamma-polymorphism (C-T polymorphism at position -158 to the Ggamma-globin gene) was studied in 13 individuals from six unrelated Pakistani families with deltabeta-thalassemia. All of the subjects had the Asian-Indian Inv/Del Ggamma(Agammadeltabeta) degrees that included six heterozygotes, six homozygotes, and one compound heterozygote of(More)
OBJECTIVE To compare the frequency of beta thalassaemia trait in individuals with Ischaemic Heart Disease (IHD) and a control population without IHD. STUDY DESIGN Case control study. PLACE AND DURATION OF STUDY Department of Haematology, Armed Forces Institute of Pathology (AFIP), Rawalpindi, from September 2007 to May 2009. METHODOLOGY Using(More)
OBJECTIVE To assess the usefulness of One Tube Osmotic Fragility Test (OTOFT) for "on the spot" screening of rural families with history of thalassaemia. METHODS It was an "observational cross-sectional" study conducted at Pathology Department of PNS Shifa Hospital, Karachi and included all available members of three families from the rural district(More)
OBJECTIVE To investigate the practices of parents of beta thalassaemia children towards utilization of prenatal diagnosis (PND) in Pakistan. METHODS A cross-sectional study was done between April and September 2007 at two thalassaemia treatment centers in Rawalpindi and Islamabad. Simple random sampling was employed to interview 215 parents of(More)
OBJECTIVE To determine the prevalence of various mutations in beta (beta) thalassaemia and its association with haematological parameters. METHODS A descriptive cross sectional study was carried out in the Department of Haematology, Armed Forced Institute of Pathology (AFIP) from February 2009 to January 2010. A total of 515 carriers having beta(More)