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The in vitro metabolism of [14C]methoxychlor (MXC), a suspected pro-oestrogenic compound, by male and female Fischer rats (F344) was compared in precision-cut liver slices. The results demonstrated time-dependent metabolism of MXC with integrated phase I and II reactions, and the sex differences were detected in the metabolic profiles. In liver slices from(More)
The in vitro metabolism of demethylated methoxychlor (MXC) metabolites, mono-OH-MXC (including (R)- and (S)-isomers) and bis-OH-MXC (mono- and bis-demethylated MXC, respectively), was conducted using precision-cut liver slices to understand the sex-dependent metabolism of MXC in rats. In the study with bis-OH-MXC, the substrate underwent extensive(More)
A multiband power amplifier using combination of CMOS and GaAs technologies (Combo MB PA) which supports quad WCDMA bands (Band V, VIII, II, I) is described. With four chips - two GaAs-HBT chips, a GaAs-HEMT chip, and a CMOS chip - mounted on a 5.5&#x00D7;5mm<sup>2</sup> laminate, the Combo MB PA comprises two amplifier chains and two SPDT HEMT band-select(More)
This paper describes a newly developed Si/GaAs hybrid multiband power amplifier module (MB-PAM) that supports major quad wideband code division multiple access (WCDMA) bands (Bands 5, 8, 2, and 1) for handset applications. With four dies (two GaAs-HBT dies, one GaAs-HEMT die, and one CMOS die) and several surface-mount devices, the hybrid MB-PAM(More)
[structure: see text] A novel TTF-based donor with a uracil moiety, TTF-(1-n-butyluracil-5-yl) (TnbU), was synthesized. Crystal structures of both TnbU and the charge-transfer complex of TnbU-hydrogen cyananilate possess complementary double hydrogen bonds through uracil moieties and pi-stacking dimer structures between TTF skeletons. Furthermore, the(More)
1. The in vitro metabolism of [14C]methoxychlor (MXC) has been studied using precision-cut liver slices from the Sprague-Dawley male rat, CD-1 male mouse, WE strain male Japanese quail and juvenile rainbow trout (Oncorhynchus mykiss). The results demonstrated integrated phase I and II metabolism of MXC and species differences in the metabolic profiles were(More)
A new stable neutral radical with intramolecular hydrogen bonding, 2,5,8-tri-tert-butyl-7-hydroxy-6-oxophenalenoxyl, was synthesized from the corresponding dihydroxyphenalenone and isolated as a stable solid under air atmosphere at room temperature. The structure was unequivocally determined by means of IR spectra, ESR/ENDOR techniques, and DFT calculations.
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