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Development and Characterization of a Clinically Compliant Xeno‐Free Culture Medium in Good Manufacturing Practice for Human Multipotent Mesenchymal Stem Cells
Human multipotent mesenchymal stem cell (MSC) therapies are currently being tested in clinical trials for Crohn's disease, multiple sclerosis, graft‐versus‐host disease, type 1 diabetes, boneExpand
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Hypoxia is a key regulator of limbal epithelial stem cell growth and differentiation.
The aim of this study was to determine whether the growth and differentiation of limbal epithelial stem cell cultures could be controlled through manipulation of the oxygen tension. Limbal epithelialExpand
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Hypoxia and adipose-derived stem cell-based tissue regeneration and engineering
Introduction: Realization that oxygen is one of the key regulators of development and differentiation has a profound significance on how current cell-based and tissue engineering applications usingExpand
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Defined xenogeneic-free and hypoxic environment provides superior conditions for long-term expansion of human adipose-derived stem cells.
Development and implementation of therapeutic protocols based on stem cells or tissue-engineered products relies on methods that enable the production of substantial numbers of cells while complyingExpand
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Online scheduling of incompatible unit-length job families with lookahead
We consider the online scheduling of incompatible unit-length job families on an unbounded parallel-batch machine with lookahead. Expand
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Online algorithms for scheduling unit length jobs on parallel-batch machines with lookahead
We consider online scheduling of unit length jobs on m parallel-batch machines with lookahead to minimize makespan. Expand
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Selective expansion of limbal epithelial stem cells in culture using hypoxia
Limbal epithelial stem cells (LESCs) maintain the corneal epithelium throughout life and are crucial for both corneal integrity and vision. In this study, LESCs were expanded in either a cultureExpand