Sudhir Singh Soam

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Binding of peptides to specific Major Histo-compatibility Complex (MHC) molecule is important for understanding immunity and has applications to vaccine discovery and design of immunotherapy. Artificial neural networks (ANN) are widely used by predictions tools to classify the peptides as binders or non-binders (BNB). However, the number of known binders to(More)
Peptide based vaccines play an important role in activating the immune response. The small peptides derived from target proteins (epitopes) of an invading pathogen, bacteria, or virus bind with the MHC molecules are recognized by CD4+ T cells or CD8+ T cells. MHC class I molecules are recognized by CD4+ T cells and MHC class – II molecules are recognized by(More)
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