Suchitra Devi Gopinath

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Expression of the key muscle transcription factor MyoD is regulated by RhoA GTPase, which is an important regulator of adhesion-dependent signaling. We show that mDiaphanous (mDia)--an adaptor protein that mediates the effects of RhoA on cell motility and the cytoskeleton--is an upstream regulator of MyoD in C2C12 mouse myoblasts. Knockdown of mDia1 reduced(More)
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