Suchismita Chandran

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Background Myostatin (MSTN), a member of the transforming growth factor beta family, negatively regulates skeletal muscle mass. Deletion of the Mstn gene results in increased muscle mass. Also, Mstn-/-mice and mice expressing a dominant negative MSTN receptor (activin receptor type IIB, ACVR2B) show decreased adipose tissue. Mstn-/-mice fed a high fat diet(More)
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