Subhashree Pradhan

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BACKGROUND Hemostasis and thrombosis are regulated by agonist-induced activation of platelet integrin alpha(IIb)beta(3). Integrin activation, in turn is mediated by cellular signaling via protein kinases and protein phosphatases. Although the catalytic subunit of protein phosphatase 1 (PP1c) interacts with alpha(IIb)beta(3), the role of PP1c in platelet(More)
Background: Hemostasis and thrombosis are regulated by agonist-induced activation of platelet integrin a IIb b 3. Integrin activation, in turn is mediated by cellular signaling via protein kinases and protein phosphatases. Although the catalytic subunit of protein phosphatase 1 (PP1c) interacts with a IIb b 3 , the role of PP1c in platelet reactivity is(More)
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