Subhadip Paul

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The organizational network changes in the human brain across the lifespan have been mapped using functional and structural connectivity data. Brain network changes provide valuable insights into the processes underlying senescence. Nonetheless, the altered network density in the elderly severely compromises the usefulness of network analysis to study the(More)
The dismal outcome of brain tumours, particularly gliomas or glioblastoma, furnishes a unique motivation for developing computational imaging and treatment planning tools that can help design the most optimal management. We present a novel scheme for simulation of radiotherapy in MRI images, by which we may visualize the changes in the tumor response. The(More)
In radiobiological models, it is often assumed that the radiation dose rate remains constant during the course of radiation delivery. However, instantaneous radiation dose rate undergoes random (stochastic) temporal fluctuation. The effect of stochastic dose rate in fractionated radiation therapy is unknown and there has been no analytical formulation of(More)
Radiation therapy is one of the important treatment procedures of cancer. The day-to-day delivered dose to the tissue in radiation therapy often deviates from the planned fixed dose per fraction. This day-to-day variation of radiation dose is stochastic. Here, we have developed the mathematical formulation to represent the day-to-day stochastic dose(More)
The efficacy of radiation therapy, a primary modality of cancer treatment, depends in general upon the total radiation dose administered to the tumour during the course of therapy. Nevertheless, the delivered radiation also irradiates normal tissues and dose escalation procedure often increases the elimination of normal tissue as well. In this article, we(More)
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