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BACKGROUND Surveillance plays a vital role in disease detection, but traditional methods of collecting patient data, reporting to health officials, and compiling reports are costly and time consuming. In recent years, syndromic surveillance tools have expanded and researchers are able to exploit the vast amount of data available in real time on the Internet(More)
The Connor-Davidson Resilience Scale (CD-RISC) is a brief self-rating questionnaire for measuring resilience. The aims of the present study were to describe the development of a Korean version of the CD-RISC (K-CD-RISC) and to more firmly establish its psychometric properties in terms of reliability and validity. The participants consisted of a general(More)
Receptor-interacting protein kinase 3 (RIPK3) functions as a key regulator of necroptosis. Here, we report that the RIPK3 expression level is negatively regulated by CHIP (carboxyl terminus of Hsp70-interacting protein; also known as STUB1) E3 ligase-mediated ubiquitylation. Chip−/− mouse embryonic fibroblasts and CHIP-depleted L929 and HT-29 cells(More)
Mapping ideas from cyberspace to realspace: visualizing the spatial context of keywords from web page search results Ming-Hsiang Tsou a , Ick-Hoi Kim a , Sarah Wandersee a , Daniel Lusher a , Li An a , Brian Spitzberg b , Dipak Gupta c , Jean Mark Gawron d , Jennifer Smith e , Jiue-An Yang a & Su Yeon Han a a Department of Geography, San Diego State(More)
Spatial interpolation is a widely used GIS function for estimating values at locations where observed values are not available or adequate. One popular method for spatial interpolation is inverse distance weighted, which calculates estimated values based on a weighted sum of the values of a number of nearest neighbors that have observed values. This(More)
Dynamic social media content, such as Twitter messages, can be used to examine individuals' beliefs and perceptions. By analyzing Twitter messages, this study examines how Twitter users exchanged and recognized toponyms (city names) for different cities in the United States. The frequency and variety of city names found in their online conversations were(More)
We developed a social media analytics and research testbed (SMART) dashboard for monitoring Twitter messages and tracking the diffusion of information in different cities. SMART dashboard is an online geo-targeted search and analytics tool, including an automatic data processing procedure to help researchers to 1) search tweets in different cities; 2)(More)
We present a novel flow mapping method called Animated Flow Mapper. Conventional flow mapping uses the thickness of a flow line to differentiate the volume of a flow and arrows to represent the direction. These flow mapping methods have suffered from problems of occlusion especially for visualizing large volumes of data, and when many flows converge at--or(More)
The tumor suppressor function of p14ARF is regulated at a posttranslational level via mechanisms yet to be fully understood. Here, we report the identification of an unconventional p14ARF degradation pathway induced by the chaperone HSP90 in association with the E3 ubiquitin ligase C-terminus of HSP70-interacting protein (CHIP). The ternary complex of(More)
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