Stuart Spechler

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In this study, a device for gastroesophageal reflux disease (GERD) monitoring has been prototyped. The system consists of an implantable, batteryless and wireless transponder with integrated impedance and pH sensors; and a wearable, external reader that wirelessly powers up the transponder and interprets the transponded radio-frequency signals. The(More)
  • Hung Cao, Vaibhav Landge, Shreyas Thakar, Smitha Rao, Lun-Chen Hsu, Shou-Jiang Tang +3 others
  • 2012
— In this work, we developed a dual-sensor system to monitor the symptoms in gastroesophageal reflux disease (GERD). The system consists of an implantable transponder and an external reader. The passive telemetry for signal transduction is based on an inductive link between two coil antennas. The reader supplies radio frequency power, obtains and stores the(More)
BACKGROUND Chronic GERD affects approximately 15% of adults in the United States and is one of the most prevalent clinical conditions involving the GI tract. The commercial tools for monitoring GERD include multichannel intraluminal impedance (MII) probes and pH-sensing capsules. However, MII probes cause discomfort, which alters patients' regular(More)
Helicobacter pylori organisms that infect the stomach conceivably could contribute to esophageal inflammation in patients with gastroesophageal reflux disease (GERD) through any of at least three potential mechanisms: 1) by causing an increase in gastric acid secretion; 2) by spreading to infect the gastric-type columnar epithelium that occasionally can(More)
BACKGROUND The incidence of esophageal adenocarcinoma (EAC) has risen rapidly in the U.S. and western world. The aim of the study was to begin the investigation of this rapid rise by developing, calibrating, and validating a mathematical disease simulation model of EAC using available epidemiologic data. METHODS The model represents the natural history of(More)
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