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OBJECTIVE To determine the impact of successive days of endurance exercise on select serum chemistry values in conditioned Alaskan sled dogs. DESIGN Prospective cohort study. ANIMALS 10 conditioned Alaskan sled dogs. PROCEDURES All dogs ran 160 km/d for 5 consecutive days. Serum was obtained prior to exercise and immediately after each exercise run;(More)
PURPOSE Team-based learning (TBL) has been successfully used in non-medical curricula, but its effectiveness in medical education has not been studied extensively. We evaluated the impact of TBL on the academic performance of Year 2 medical students at Wright State University by comparing this active learning strategy against a traditional method of(More)
New and established embryoid lines of oil palm (Elaeis guineensis Jacq.) clones, classified with regard to the expected risk of mantled flowering, were included in experiments to determine to what extent culture conditions during 48 weeks of embryoid multiplication could influence the incidence and severity of mantled flowering. Variables tested included(More)
Goal is to investigate how delivery nozzle design influences the cooling rate of cryogen spray as used in skin laser treatments. Cryogen was sprayed through nozzles that consist of metal tubes with either a narrow or wide diameter and two different lengths. Fast-flashlamp photography showed that the wide nozzles, in particular the long wide one, produced a(More)
—Cryogen spray cooling (CSC) has been used for selective epidermal cooling of human skin during laser therapy of patients with port wine stain (PWS) birthmarks. Unfortunately , current commercial CSC devices do not provide optimal cooling selectivity and, therefore, provide insufficient epidermal protection for some PWS patients. To assist in the(More)
PURPOSE Since team-based learning (TBL) was introduced as a medical education strategy in 2001, few studies have explored its impact on learning outcomes, particularly as measured by performance on examinations. Educators considering implementing TBL need evidence of its effectiveness. This study was conducted to determine whether student performance on(More)
Background and Objectives: Application of local vacuum pressure to human skin during laser irradiation results in less absorption in the epidermis and more light delivered to targeted vessels with an increased blood volume. The objective of the present numerical study is to assess the effect of applying local vacuum pressure on the temperatures of the(More)
Heat transfer rate at the skin-air interface is of critical importance for the benefits of cryogen spray cooling in combination with laser therapy of shallow subsurface skin lesions, such as port-wine stain birthmarks. With some cryogen spray devices, a layer of liquid cryogen builds up on the skin surface during the spurt, which may impair heat transfer(More)
The orally active microtubule-disrupting agent (S)-1-ethyl-3-(2-methoxy-4-(5-methyl-4-((1-(pyridin-3-yl)butyl)amino)pyrimidin-2-yl)phenyl)urea (CYT997), reported previously by us (Bioorg Med Chem Lett 19:4639-4642, 2009; Mol Cancer Ther 8:3036-3045, 2009), is potently cytotoxic to a variety of cancer cell lines in vitro and shows antitumor activity in vivo.(More)