The effects of chronically ablating the serotoninergic inputs to various regions of the rat brain on the ability to solve a feature-negative discrimination was measured. After intracerebroventricular administration of the specific neurotoxin 5,7-dihydroxytryptamine, the rats exhibited an impaired capacity to solve such a discrimination, irrespective of… (More)
Auditory evoked potentials to tone stimuli were recorded from 8 practised meditators before, during, and after meditation, and also during light sleep. No consistent changes were noted between baseline and meditating AEPs, or between meditating and sleep AEPs.
This article considers recent policing and regulatory responses to the night-time economy in England and Wales. Drawing upon the findings of a broader two-year qualitative investigation of local and national developments in alcohol policy, it identifies a dramatic acceleration of statutory activity, with 12 new or revised powers, and several more in… (More)
Small doses of clonidine produce hypoactivity in mice and rats, probably by stimulating pre-synaptic alpha 2-adrenoceptors in the brain. When mice were injected with desmethylimipramine (DMI, 5 mg/kg) before clonidine it attenuated the hypoactivity, while pretreatment with amitriptyline (5 mg/kg) or mianserin (5 mg/kg) potentiated this behaviour. In rats,… (More)