Stine Bjørn Kristensen

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Paraneoplastic syndromes (PNS) are relatively infrequent manifestations appearing before or after a cancer declares itself. Autoimmune mechanisms may be involved, but their cause and pathogenesis are often unknown. Due to disparity of symptoms, PNS remain a major diagnostic challenge. We examined the value of FDG-PET/CT for ruling in or out malignancy in a(More)
SSX cancer/testis antigens are frequently expressed in melanoma tumors and represent attractive targets for immunotherapy, but their role in melanoma tumorigenesis has remained elusive. Here, we investigated the cellular effects of SSX2 expression. In A375 melanoma cells, SSX2 expression resulted in an increased DNA content and enlargement of cell nuclei,(More)
Sir, We thank Vatankulu et al. [1] for their interest in our recent paper in the European Journal of Nuclear Medicine and Molecular Imaging on FDG PET/CT in patients with suspected paraneoplastic syndromes (PNS) [2]. As discussed in their comment, the paraneoplastic antibodies may have some merit in certain settings, but also seem controversial as addressed(More)
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