Stewart W. Church | Semantic Scholar

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Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors.

S. E. Hilary Russell, Michael A Mcilhatton, +12 authors Peter G. Johnston
Cancer research
2000

Allele losses from chromosome 17 are common in sporadic ovarian tumors. Previously, we reported high rates of LOH (up to 70%) from 17q25 at the marker THH59 in a bank of malignant ovarian tumors. We… (More)

Properties of SEPT9 isoforms and the requirement for GTP binding.

C. A. Robertson, Stewart W. Church, Hans A Nagar, John K. Price, Peter Alec Hall, S. E. Hilary Russell
The Journal of pathology
2004

Members of the evolutionarily conserved septin family of genes are emerging as key components of several cellular processes including membrane trafficking, cytokinesis, and cell-cycle control events.… (More)

Methylation status of oestrogen receptor-α gene promoter sequences in human ovarian epithelial cell lines

Alan M. O'Doherty, Stewart W. Church, S. E. Hilary Russell, J. Nelson, Ivor Hickey
British Journal of Cancer
2002

We have determined the methylation status of the CpG island of the oestrogen receptor α gene in seven human ovarian cell lines. Cell lines expressing oestrogen receptor α showed no evidence of… (More)

Advances in Brief Isolation and Mapping of a Human Septin Gene to a Region on Chromosome 17 q , Commonly Deleted in Sporadic Epithelial Ovarian Tumors 1

S. E. Hilary Russell, Michael A Mcilhatton, +12 authors Patrick Gerard Johnston
2000

Expression of the SEPT9_i4 isoform confers resistance to microtubule-interacting drugs

Alex D. Chacko, Simon S McDade, +5 authors S. E. Hilary Russell
Cellular Oncology
2005

BackgroundThe evolutionarily conserved septin family of genes encode GTP binding proteins involved in a variety of cellular functions including cytokinesis, apoptosis, membrane dynamics and vesicle… (More)

Combination of 5-fluorouracil and irinotecan on modulation of thymidylate synthase and topoisomerase I expression and cell cycle regulation in human colon cancer LoVo cells: clinical relevance.

Jian-Ming Xu, Amalia Azzariti, +5 authors Angelo Paradiso
Clinical colorectal cancer
2002

This study was designed to explore the possible interaction of 5-fluorouracil (5-FU) and 7-ethyl-10-hydroxycamptothecin (SN-38) in vitro. Human colon cancer LoVo cells were treated in both a dose-… (More)