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- S N Ethier, T Nagylaki
- Journal of mathematical biology
- 1989

Diffusion approximations are established for the multiallelic, two-locus Wright-Fisher model for mutation, selection, and random genetic drift in a finite, panmictic, monoecious, diploid population. All four combinations of weak or strong selection and tight or loose linkage are treated, though the proof in the case of strong selection and loose linkage is… (More)

Using duality, an expansion is found for the transition function of the reversible $K$-allele diffusion model in population genetics. In the neutral case, the expansion is explicit but already known. When selection is present, it depends on the distribution at time $t$ of a specified $K$-type birth-and-death process starting at "infinity". The latter… (More)

- S N Ethier, S E Hodge
- American journal of medical genetics
- 1985

This study considers configurations of identity-by-descent sharing in sibships as an alternative to breaking the sibship into sib pairs. A general method is presented for specifying all distinct configurations and deriving their probabilities. The method works for sibships of arbitrary size and can be implemented with paper and pencil. Specific results are… (More)

- S. N. Ethier
- 2014

Petrov constructed a diffusion process in the compact Kingman simplex whose unique stationary distribution is the two-parameter Poisson–Dirichlet distribution of Pitman and Yor. We show that the subset of the simplex comprising vectors whose coordinates sum to 1 is the natural state space for the process. In fact, the complementary set acts like an entrance… (More)

- W J Ewens, R C Griffiths, S N Ethier, S A Wilcox, J A Graves
- Genomics
- 1992

There are many situations in which grain distributions resulting from in situ hybridization of radioactively labeled probes to unique genes should be subjected to a statistical analysis. However, the problems posed by analysis of in situ hybridization data are not straightforward, and no completely satisfying method is currently available. We have developed… (More)

- S N Ethier, M F Norman
- Proceedings of the National Academy of Sciences…
- 1977

The Wright--Fisher model and its approximating diffusion model are compared in terms of the expected value of a smooth but arbitrary function of nth-generation gene frequency. In the absence of selection, this expectation is shown to differ in the two models by at most a linear combination (with coefficients depending only on the derivatives of the smooth… (More)

Consider a wager that is more complicated than simply winning or losing the amount of the bet. For example, a pass line bet with double odds is such a wager, as is a bet on video poker using a specified drawing strategy. We are concerned with the probability that, in an independent sequence of identical wagers of this type, the gambler loses L or more… (More)

- S. N. Ethier, Jiyeon Lee
- 2008

That there exist two losing games that can be combined, either by random mixture or by nonrandom alternation, to form a winning game is known as Parrondo’s paradox. We establish a strong law of large numbers and a central limit theorem for the Parrondo player’s sequence of profits, both in a one-parameter family of capital-dependent games and in a… (More)

- Stewart N. Ethier, Jiyeon Lee
- ArXiv
- 2014

We study Toral’s Parrondo games with N players and one-dimensional spatial dependence as modified by Xie et al. Specifically, we use computer graphics to sketch the Parrondo and anti-Parrondo regions for 3 ≤ N ≤ 9. Our work was motivated by a recent paper of Li et al., who applied a state space reduction method to this model, reducing the number of states… (More)

- S. N. Ethier, Jiyeon Lee
- 2012

In Toral’s games, at each turn one member of an ensemble of N ≥ 2 players is selected at random to play. He plays either game A′, which involves transferring one unit of capital to a second randomly chosen player, or game B, which is an asymmetric game of chance whose rules depend on the player’s current capital, and which is fair or losing. Game A′ is fair… (More)