Steven Y. P. Lu

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Queen's University for their helpful comments. Andrew Ching would like to acknowledge research support from the Connaught New-staff Matching grant at the University of Toronto. The views expressed in this paper are those of the authors and do not necessarily reflect those of the Federal Reserve Bank of Kansas City or the Federal Reserve System. Abstract By(More)
The Kemp elimination is prototypical reaction used to study proton abstraction from carbon. Several hydrophobic systems are known to accelerate this reaction, including two classes of computationally-designed enzymes. However, it is unclear whether these computationally-designed enzymes establish specific interactions with their substrates, as natural(More)
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