Steven S. Gans

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BACKGROUND Ramucirumab is a human IgG1 monoclonal antibody that targets the extracellular domain of VEGFR-2. We aimed to assess efficacy and safety of treatment with docetaxel plus ramucirumab or placebo as second-line treatment for patients with stage IV non-small-cell-lung cancer (NSCLC) after platinum-based therapy. METHODS In this multicentre,(More)
New reasoning techniques for dealing with uncertainty in expert systems have been embedded in RUM, a Reasoning with Uncertainty Module. RUM is an integrated software tool based on a frame system (KEE) that is implemented in an object oriented language. RUM's capabilities are subdivided into three layers: representation, inference, and control. The(More)
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