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CONTEXT Despite evidence that patients with acute lung injury (ALI) have pulmonary surfactant dysfunction, trials of several surfactant preparations to treat adults with ALI have not been successful. Preliminary studies in children with ALI have shown that instillation of a natural lung surfactant (calfactant) containing high levels of surfactant-specific(More)
OBJECTIVES To determine the current mortality rates for pediatric patients with septic shock and the frequency and outcome of associated multiple organ system failure. DESIGN Retrospective chart review. SETTING Multidisciplinary pediatric intensive care unit. PATIENTS Children age 1 month to 21 yrs admitted to the pediatric intensive care unit from(More)
(Dual-)promotion and (dual-)evacuation are bijections on SY T (λ) for any partition λ. Let cr denote the rectangular partition (c, . . . , c) of height r, and let sck (k > 2) denote the staircase partition (k, k−1, . . . , 1). We demonstrate a promotionand evacuation-preserving embedding of SY T (sck) into SY T (k k+1). We hope that this result, together(More)
The onset of symptomatic hypoglycemia in children with ingestions of second-generation sulfonylureas has never been documented to be later than 21 hours post-ingestion. We report a case with the longest known interval, 45 hours, between ingestion of a sulfonylurea and the onset of hypoglycemia requiring medical intervention. The hypoglycemia was severe and(More)
The treatment of complex parapneumonic effusions in children remains controversial, with some advocating less invasive, strictly medical management and others supporting a more aggressive approach of thoracotomy with or without decortication. Recent advances, including video-assisted thoracoscopic surgery and intrapleural fibrinolytic therapy, offer new(More)
OBJECTIVE To assess the impact of calfactant (a modified natural bovine lung surfactant) in immunocompromised children with acute lung injury and to determine the number of patients required for a definitive clinical trial of calfactant in this population. DESIGN Post hoc analysis of data from a previous randomized, control trial. SETTING Tertiary care(More)
OBJECTIVE To evaluate the intraoperative and postoperative care of children following thoracoabdominal resection of neuroblastoma. DESIGN Retrospective chart review. SETTING Pediatric intensive care unit (PICU) of major pediatric cancer center. PATIENTS Eighty-eight patients undergoing thoracoabdominal resection of neuroblastoma over a 6-year period.(More)
BACKGROUND Physicians caring for children with serious acute neurologic disease must process overwhelming amounts of physiological and medical information. Strategies to optimize real time display of this information are understudied. OBJECTIVES Our goal was to engage clinical and engineering experts to develop guiding principles for creating a pediatric(More)
We introduce affine Stanley symmetric functions for the special orthogonal groups, a class of symmetric functions that model the cohomology of the affine Grassmannian, continuing the work of Lam and Lam, Schilling, and Shimozono on the special linear and symplectic groups, respectively. For the odd orthogonal groups, a Hopf-algebra isomorphism is given,(More)