Steven P. Anderson

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During the TOGA COARE Intensive Observing Period (IOP) from November 1992 through February 1993, temperature, salinity, and velocity profiles were repeatedly obtained within a 130 km ϫ 130 km region near the center of the Intensive Flux Array (IFA) in the western equatorial Pacific warm pool. Together with high quality measurements of air–sea heat flux,(More)
Fibrates, such as ciprofibrate, fenofibrate, and clofibrate, are peroxisome proliferator-activated receptor-alpha (PPARalpha) agonists that have been in clinical use for many decades for treatment of dyslipidemia. When mice and rats are given PPARalpha agonists, these drugs cause hepatic peroxisome proliferation, hypertrophy, hyperplasia, and eventually(More)
Our long-term goal is to identify and understand the dominant vertical mixing processes influencing the evolution of the stratification over continental shelves. OBJECTIVES We want to understand the dynamics of the surface and bottom boundary layers over continental shelves and how the boundary layers contribute to mixing and the evolution of the(More)
Chronic exposure to peroxisome proliferators (PPs) leads to increased incidence of liver tumors in rodents. Liver tumor induction is thought to require increased hepatocyte proliferation and suppression of apoptosis. Transcript profiling showed increased expression of proapoptotic genes and decreased expression of antiapoptotic genes in the livers of mice(More)
Background: The nuclear receptor peroxisome proliferator-activated receptor alpha (PPARa) regulates responses to chemical or physical stress in part by altering expression of genes involved in proteome maintenance. Many of these genes are also transcriptionally regulated by heat shock (HS) through activation by HS factor-1 (HSF1). We hypothesized that there(More)
Chronic exposure to peroxisome proliferators (PP), including certain industrial and pharmaceutical chemicals, causes liver cancer in rodents. Continuous exposure to PP is needed for tumor development since the frequency of hepatocellular neoplasms is decreased in animals returned to control diet. To determine cellular and molecular events responsible for(More)
Coastal ocean models often rely on the surface fields from numerical weather prediction (NWP) models for realistic surface boundary conditions, but the errors in these fields are poorly understood. We evaluate the surface meteorological and flux fields provided by three of the regional NWP models in operation during 1996 and 1997 at the U.S. National(More)
  • P. Burns, Djamal Khelif, +8 authors Chris W. Fairall
  • 1998
Comparisons of mean ambient temperature, speciic humidity, static pressure, and horizontal wind from the ve Tropical Ocean-Global Atmosphere Coupled Ocean-Atmosphere Response Experiment (TOGA COARE) boundary-layer aircraft were obtained from 38 two-and three-aircraft, close-formation, level runs. These, together with consideration of surface measurements(More)
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