• Publications
  • Influence
A Theoretically Based Index of Consciousness Independent of Sensory Processing and Behavior
An electroencephalographic-derived index of human consciousness that reflects the information content of the brain’s response to a magnetic stimulus is defined, and appears to be a robust measure that distinguishes conscious from unconscious states well enough to be used on an individual basis, a prerequisite for deployment in the clinic. Expand
Diagnostic accuracy of the vegetative and minimally conscious state: Clinical consensus versus standardized neurobehavioral assessment
Standardized neurobehavioral assessment is a more sensitive means of establishing differential diagnosis in patients with disorders of consciousness when compared to diagnoses determined by clinical consensus. Expand
Brain function in coma, vegetative state, and related disorders
We review the nosological criteria and functional neuroanatomical basis for brain death, coma, vegetative state, minimally conscious state, and the locked-in state. Functional neuroimaging isExpand
Detecting Awareness in the Vegetative State
Functional magnetic resonance imaging was used to demonstrate preserved conscious awareness in a patient fulfilling the criteria for a diagnosis of vegetative state and the patient activated predicted cortical areas in a manner indistinguishable from that of healthy volunteers. Expand
The neural correlate of (un)awareness: lessons from the vegetative state
  • Steven Laureys
  • Medicine, Psychology
  • Trends in Cognitive Sciences
  • 1 December 2005
Functional neuroimaging results have shown that some parts of the cortex are still functioning in 'vegetative' patients but these areas are functionally disconnected from 'higher order' associative areas needed for awareness. Expand
Baseline brain activity fluctuations predict somatosensory perception in humans
Results indicate a positive relationship between conscious perception of low-intensity somatosensory stimuli and immediately preceding levels of baseline activity in medial thalamus and the lateral frontoparietal network, respectively, which are thought to relate to vigilance and “external monitoring". Expand
Disorders of consciousness after acquired brain injury: the state of the science
The state of the science with regard to clinical management of patients with prolonged disorders of consciousness is described, and consciousness-altering pathophysiological mechanisms, specific clinical syndromes, and novel diagnostic and prognostic applications of advanced neuroimaging and electrophysiological procedures are reviewed. Expand
Are Spatial Memories Strengthened in the Human Hippocampus during Slow Wave Sleep?
It is shown that, in humans, hippocampal areas that are activated during route learning in a virtual town are likewise activated during subsequent slow wave sleep, and that the amount of hippocampal activity expressed during slow waveSleep positively correlates with the improvement of performance in route retrieval on the next day. Expand
Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients.
It is shown that default network connectivity is decreased in severely brain-damaged patients, in proportion to their degree of consciousness impairment, as well as in healthy controls and locked-in syndrome patients. Expand
Breakdown of within- and between-network Resting State Functional Magnetic Resonance Imaging Connectivity during Propofol-induced Loss of Consciousness
It is suggested that propofol-induced unconsciousness could be linked to a breakdown of cerebral temporal architecture that modifies both within- and between-network connectivity and thus prevents communication between low-level sensory and higher-order frontoparietal cortices, thought to be necessary for perception of external stimuli. Expand