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A Theoretically Based Index of Consciousness Independent of Sensory Processing and Behavior
An electroencephalographic-derived index of human consciousness that reflects the information content of the brain’s response to a magnetic stimulus is defined, and appears to be a robust measure that distinguishes conscious from unconscious states well enough to be used on an individual basis, a prerequisite for deployment in the clinic.
Brain function in coma, vegetative state, and related disorders
Diagnostic accuracy of the vegetative and minimally conscious state: Clinical consensus versus standardized neurobehavioral assessment
Standardized neurobehavioral assessment is a more sensitive means of establishing differential diagnosis in patients with disorders of consciousness when compared to diagnoses determined by clinical consensus.
Baseline brain activity fluctuations predict somatosensory perception in humans
- M. Boly, E. Balteau, Steven Laureys
- Psychology, BiologyProceedings of the National Academy of Sciences
- 17 July 2007
Results indicate a positive relationship between conscious perception of low-intensity somatosensory stimuli and immediately preceding levels of baseline activity in medial thalamus and the lateral frontoparietal network, respectively, which are thought to relate to vigilance and “external monitoring".
From unresponsive wakefulness to minimally conscious PLUS and functional locked-in syndromes: recent advances in our understanding of disorders of consciousness
- M. Bruno, A. Vanhaudenhuyse, A. Thibaut, G. Moonen, Steven Laureys
- Psychology, BiologyJournal of Neurology
- 16 June 2011
An improved assessment of brain function in coma and related states is not only changing nosology and medical care but also offers a better-documented diagnosis and prognosis and helps to further identify the neural correlates of human consciousness.
Detecting awareness in the vegetative state.
- A. Owen, M. Coleman, M. Boly, Matthew H. Davis, Steven Laureys, J. Pickard
- 8 September 2006
Functional magnetic resonance imaging was used to demonstrate preserved conscious awareness in a patient fulfilling the criteria for a diagnosis of vegetative state and the patient activated predicted cortical areas in a manner indistinguishable from that of healthy volunteers.
Are Spatial Memories Strengthened in the Human Hippocampus during Slow Wave Sleep?
Experience-dependent changes in cerebral activation during human REM sleep
Using positron emission tomography and regional cerebral blood flow measurements, it is shown that waking experience influences regional brain activity during subsequent sleep and supports the hypothesis that memory traces are processed during REM sleep in humans.
The neural correlate of (un)awareness: lessons from the vegetative state
- Steven Laureys
- Psychology, BiologyTrends in Cognitive Sciences
- 1 December 2005
Disorders of consciousness after acquired brain injury: the state of the science
- J. Giacino, J. Fins, Steven Laureys, N. Schiff
- Medicine, PsychologyNature Reviews Neurology
- 1 February 2014
The state of the science with regard to clinical management of patients with prolonged disorders of consciousness is described, and consciousness-altering pathophysiological mechanisms, specific clinical syndromes, and novel diagnostic and prognostic applications of advanced neuroimaging and electrophysiological procedures are reviewed.