Steven K. Albanese

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Genomic studies have linked mTORC1 pathway-activating mutations with exceptional response to treatment with allosteric inhibitors of mTORC1 called rapalogs. Rapalogs are approved for selected cancer types, including kidney and breast cancers. Here, we used sequencing data from 22 human kidney cancer cases to identify the activating mechanisms conferred by(More)
Salinomys delicatus is considered a rare species due to its restricted and patchy distribution, poor records and low abundances. It is also the phyllotine with the lowest known diploid chromosome number (2n = 18), however its sex chromosome system has never been described. Here, we studied the chromosomes of six females and three males with bands G, C,(More)
Daniel L. Parton,1 Sonya M. Hanson,1 Lucelenie Rodríguez-Laureano,1 Steven K. Albanese,2 2 Scott Gradia,3 Chris Jeans,3 Markus Seeliger,4 Nicholas Levinson,5 and John D. Chodera1, ∗ 3 1Computational Biology Program, Sloan Kettering Institute, 4 Memorial Sloan Kettering Cancer Center, New York, NY 10065† 5 2Gerstner Sloan Kettering Graduate School, Memorial(More)
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