Steven J. Lade

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Critical transitions are sudden, often irreversible, changes that can occur in a large variety of complex systems; signals that warn of critical transitions are therefore highly desirable. We propose a new method for early warning signals that integrates multiple sources of information and data about the system through the framework of a generalized model.(More)
Ecological regime shifts are rarely purely ecological. Not only is the regime shift frequently triggered by human activity, but the responses of relevant actors to ecological dynamics are often crucial to the development and even existence of the regime shift. Here, we show that the dynamics of human behaviour in response to ecological changes can be(More)
Asymmetric segregation of damaged proteins at cell division generates a cell that retains damage and a clean cell that supports population survival. In cells that divide asymmetrically, such as Saccharomyces cerevisiae, segregation of damaged proteins is achieved by retention and active transport. We have previously shown that in the symmetrically dividing(More)
Investigations into molecular motor dynamics are increasingly focused on small-scale features of the motor's motion. We define performance measures of a common type of single-molecule motility assay, the bead assay, for its ability to detect such features. Using numerical models, we explore the dependence of assay performance on a number of experimentally(More)
Modeling social-ecological systems is difficult due to the complexity of ecosystems and of individual and collective human behavior. Key components of the social-ecological system are often oversimplified or omitted. Generalized mod-eling is a dynamical systems approach that can overcome some of these challenges. It can analyze qualitative system dynamics(More)
Kramers-Moyal coefficients provide a simple and easily visualized method with which to analyze nonlinear stochastic time series. One mechanism that can affect the estimation of the coefficients is geometric projection effects. For some biologically inspired examples, these effects are predicted and explored with a nonstochastic projection operator method(More)
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