Steven G. Hege

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Abecarnil is a metabolically stable β-carboline that binds with high affinity and selectivity to central benzodiazepine receptors. The effects on cognitive and psychomotor skills of abecarnil (ZK 112–119), 2.5 mg and 5.0 mg, were compared with lorazepam 2.0 mg and placebo. Twenty-four healthy, young males participated in a double-blind, four-way Latin(More)
Effects of aging on ethyl alcohol (EtOH) pharmacodynamics were examined over progressive dosing schedules (0.4, 0.6, 0.8, 1.0 g/kg) in groups of young (25.0±2.9 years), middle-aged (41.1±6.6 years), and young-elderly adults (60.9±2.6 years) using three computerized cognitive-neuromotor tasks: digitsymbol substitution (DSS), keypad reaction time (KRT), and(More)
Eight healthy young males were administered single doses of lorazepam (4 mg), clonazepam (4 mg), alprazolam (2 mg) or placebo, and their performance on behavioral tasks was monitored for 7 h. Lorazepam and clonazepam impaired performance on subcritical tracking, a primarily neuromotor task, for 2-4 h longer than alprazolam. Although the duration of(More)
Venöse Malformationen als Ursache einer Raumforderung im Kopf-Hals-Bereich sind, besonders im fortgeschrittenen Lebensalter, selten. Wir berichten im Folgenden über eine 74-jährige Patientin mit einer venösen Malformation der Wange und die erfolgreiche chirurgische Therapie. Venous malformations as a cause of space-occupying lesions in the head and neck(More)
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