Steven E. Domino

Learn More
BACKGROUND Cilia are specialized organelles that play a fundamental role in several mammalian processes including left-right axis determination, sperm motility, and photoreceptor maintenance. Mutations in cilia-localized proteins have been linked to human diseases including cystic kidney disease and retinitis pigmentosa. Retinitis pigmentosa can be caused(More)
Angiogenesis plays an important role in wound healing and tumor growth. Fucosyltransferases synthesize fucosylated glycans and may play a major role in vascular biology. To examine the role of an alpha(1,2) fucosyltransferase (Fut2) in angiogenesis. We found that Fut2 mRNA and protein expression is inducible in human dermal microvascular endothelial cells(More)
  • 1