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Attenuation of the neural response to sad faces in major depression by antidepressant treatment: a prospective, event-related functional magnetic resonance imaging study.
- C. Fu, Steven C. R. Williams, E. Bullmore
- Psychology, MedicineArchives of general psychiatry
- 1 September 2004
Antidepressant treatment reduces left limbic, subcortical, and neocortical capacity for activation in depressed subjects and increases the dynamic range of the left prefrontal cortex.
Social intelligence in the normal and autistic brain: an fMRI study
- S. Baron-Cohen, H. Ring, Steven C. R. Williams
- Psychology, BiologyThe European journal of neuroscience
- 1 June 1999
Functional magnetic resonance imaging (fMRI) confirmed Brothers' prediction that the STG and amygdala show increased activation when using social intelligence, and provided support for the social brain theory of normal function, and the amygdala theory of autism.
Mapping Motor Inhibition: Conjunctive Brain Activations across Different Versions of Go/No-Go and Stop Tasks
Increased BOLD signal was observed in left hemispheric dorsolateral prefrontal, medial, and parietal cortices during the go/no-go task, presumably reflecting a left frontoparietal specialization for response selection.
Atlasing location, asymmetry and inter-subject variability of white matter tracts in the human brain with MR diffusion tractography
Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder.
- M. Kempton, J. Geddes, U. Ettinger, Steven C. R. Williams, P. Grasby
- PsychologyArchives of general psychiatry
- 1 September 2008
The meta-analyses revealed robust but regionally nonspecific changes of brain structure in bipolar disorder and revealed individual studies will remain underpowered unless sample size is increased or improvements in phenotypic selection and imaging methods are made to reduce within-study heterogeneity.
Neural Responses to Sad Facial Expressions in Major Depression Following Cognitive Behavioral Therapy
How Good Is Good Enough in Path Analysis of fMRI Data?
- E. Bullmore, B. Horwitz, G. Honey, M. Brammer, Steven C. R. Williams, T. Sharma
- 1 April 2000
A model including unidirectional connections from frontal to parietal cortex, designed to represent sequential engagement of rehearsal and monitoring components of the articulatory loop, is found to be irrefutable by hypothesis-testing and within confidence limits for the best model that could be fitted to the data.
A functional MRI study of happy and sad affective states induced by classical music
- M. Mitterschiffthaler, C. Fu, Jeffrey A Dalton, C. Andrew, Steven C. R. Williams
- PsychologyHuman brain mapping
- 1 November 2007
The findings suggest that an emotion processing network in response to music integrates the ventral and dorsal striatum, areas involved in reward experience and movement; the anterior cingulate, which is important for targeting attention; and medial temporal areas, traditionally found in the appraisal and processing of emotions.
Amygdala, hippocampal and corpus callosum size following severe early institutional deprivation: the English and Romanian Adoptees study pilot.
- M. Mehta, Nicole I Golembo, E. Sonuga-Barke
- Psychology, BiologyJournal of child psychology and psychiatry, and…
- 1 August 2009
The adoption into the UK of children who have been reared in severely deprived conditions provides an opportunity to study possible association between very early negative experiences and subsequent brain development and the need for future studies to confirm the sensitivity of the amygdala to early deprivation.
Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder.
- M. Kempton, Zainab Salvador, Steven C. R. Williams
- Psychology, BiologyArchives of general psychiatry
- 4 July 2011
The meta-analyses revealed structural brain abnormalities in MDD that are distinct from those observed in BD, and may aid investigators attempting to discriminate mood disorders using structural magnetic resonance imaging data.