To investigate the effects of exercise training and immobilization on peak O2 uptake (VO2) and effective O2 diffusive conductance (DO2) in skeletal muscle, three groups of purpose-bred hounds… (More)
Data from eighteen subjects, studied in hypoxia (minimum PIO2 = 80 Torr) both at rest and during exercise, were analyzed using computer models which estimate O2 diffusing capacity from measured VA/Q… (More)
Intrapulmonary chemoreceptors (IPC) are CO(2)-sensitive sensory neurons that innervate the lungs of birds, help control the rate and depth of breathing, and require carbonic anhydrase (CA) for normal… (More)
Intrapulmonary chemoreceptors (IPC) are neurons that sense tonic and phasic CO2 stimuli in the lungs of birds and diapsid reptiles. IPC are different from most other vertebrate respiratory CO2… (More)
Because chemicals introduced into the environment by humans can affect both long-term survivorship and reproduction of amphibians, discovering the specific mechanisms through which these chemicals… (More)
The majority of patients with intrapulmonary right-to-left shunting due to pulmonary arteriovenous malformations-exhibit good maximum exercise capacity (> 70% predicted) despite profound arterial… (More)
Chronic hypoxic acclimatization modifies ventilatory reflexes arising from carotid body stimulation. To explore this, the effects of in vivo chronic hypoxia on membrane currents were quantified in… (More)
We quantified the neural discharge of intrapulmonary chemoreceptors (IPC) innervating the left lungs of anesthetized Pekin ducks. Right and left lungs were separately unidirectionally ventilated.… (More)
Inert gas elimination studies in interstitial fibrosis ascribe all of the resting and most (58-83%) of the exercise (A-a)PO2 difference to ventilation-perfusion inequality. The previous paper… (More)