Steven Breakspear

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BACKGROUND Human hair cuticle is always exposed to various stresses and then gradually lost in daily life. There are two typical patterns of cuticle damage: type L, where the cell membrane complex, the structure located between cuticle cells, is split and the cuticle lifts up, and type E, where the fragile substructure of the cuticle cell (endocuticle) is(More)
Thick and coarse hair, as typically found among the Japanese population, frequently lacks softness that consumers are acutely aware of. Such poor feeling is accentuated by daily grooming, weathering, and chemical treatments, in particular, which can cause changes in the hair shape and the creation of frizzy or irregularly shaped hair. Existing technologies(More)
The effects of Sox21 gene deletion on hair lipids have been studied. For the cuticle-specific bound lipid 18-methyl eicosanoic acid (18-MEA), which was found to predominantly exist as the free form in Sox21(-/-) hair, total levels and distribution were unexpectedly unchanged. This indicates that while the biosynthesis of 18-MEA is unaffected, its covalent(More)
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