Steven B. Heymsfield

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BACKGROUND The manner in which fat depot volumes and distributions, particularly the adipose tissue (AT) between the muscles, vary by race is unknown. OBJECTIVE The objective was to quantify a previously unstudied and novel intermuscular AT (IMAT) depot and subcutaneous AT, visceral AT (VAT), and total-body skeletal muscle mass in healthy sedentary(More)
In 2008 the National Center for Health Statistics released a dual energy x-ray absorptiometry (DXA) whole body dataset from the NHANES population-based sample acquired with modern fan beam scanners in 15 counties across the United States from 1999 through 2004. The NHANES dataset was partitioned by gender and ethnicity and DXA whole body measures of %fat,(More)
Accurate quantification of total body and the distribution of regional adipose tissue using manual segmentation is a challenging problem due to the high variation between manual delineations. Manual segmentation also requires highly trained experts with knowledge of anatomy. We present a hybrid segmentation method that provides robust delineation results(More)
BACKGROUND Despite increasing research and clinical significance, limited information is available on how the visceral and subcutaneous adipose tissue (VAT and SAT) compartments develop during growth and maturation and then vary in volume across the adult lifespan. The present study aimed at exploring how adipose tissue compartments partition across the(More)
Although specialized cortical pathways that process specific sensory stimuli and/or execute cognitive functions have been identified, the neuro-specificity for food-related stimuli has not been clearly demonstrated. We employed functional magnetic resonance imaging (fMRI) to compare neural systems associated with the appreciation of foods and nonfoods.(More)
BACKGROUND Even though skeletal muscle (SM) is the largest body compartment in most adults and a key phenotypic marker of sarcopenia and cachexia, SM mass was until recently difficult and often impractical to quantify in vivo. This review traces the historical development of SM mass measurement methods and their evolution to advances that now promise to(More)
OBJECTIVE Although widely applied as a phenotypic expression of adiposity in population and gene-search studies, body mass index (BMI) is also acknowledged to reflect muscularity even though relevant studies directly measuring skeletal muscle (SM) mass are lacking. The current study aimed to fill this important gap by applying advanced imaging methods to(More)
BACKGROUND It is unknown whether regional measures of skeletal muscle (SM) in the thigh and abdomen accurately reflect whole-body SM mass. OBJECTIVE We aimed to determine whether thigh and abdominal SM measures reflect whole-body SM mass and, if so, which region is a stronger marker. DESIGN Whole-body and regional measures of SM were obtained by(More)
OBJECTIVE To develop a new geometrical index that combines height, waist circumference (WC), and hip circumference (HC) and relate this index to total and visceral body fat. DESIGN AND METHODS Subject data were pooled from three databases that contained demographic, anthropometric, dual energy X-ray absorptiometry (DXA) measured fat mass, and magnetic(More)
BACKGROUND/OBJECTIVES Recent research has shown an inverse relationship between bone marrow adipose tissue (BMAT) and bone mineral density (BMD). There is a lack of evidence at the macro-imaging level to establish whether increased BMAT is a cause or effect of bone loss. This cross-sectional study compared the BMAT and BMD relationship between a younger(More)