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43 G ameBots [1] is a virtual reality platform that allows the creation and evaluation of intelligent agents that interact with a rich 3D continuous dynamic environment. As opposed to previous test beds that focus on a single task and environment (such as soccer simulation [4]), GameBots does not define a single benchmark task. Instead, the GameBots(More)
CL 277,082 (I) was found to be a potent inhibitor of acyl CoA:cholesterol acyltransferase (ACAT, EC 2.3.1.26) in microsomes from a variety of tissues with IC50 values of 0.14 microM for intestinal mucosal microsomes, 0.74 microM for liver, and 1.18 microM for rat adrenal. I was also shown to inhibit ACAT in cultured smooth muscle cells (IC50 = 0.8 microM)(More)
OBJECTIVE To examine the association between breast cancer risk and the fatty acid composition of phospholipids in prediagnostic serum samples. METHODS We analyzed the fatty acid composition in 130 incident postmenopausal breast cancer cases and 257 matched controls nested within the beta-Carotene and Retinol Efficacy Trial Cohort. The fatty acid(More)
BACKGROUND Only limited data is available on the frequency and clinical significance of very low hepatitis C viremia (<600 IU/ml) determined by novel sensitive methods for HCV quantification. STUDY DESIGN We evaluated the new Abbott m2000 RealTime PCR assay in 3213 consecutive anti-HCV-positive sera as well as in 50 HCV-recovered patients with sustained(More)
Biomarkers of trans-fatty acid consumption have been associated with increased risks of breast and colon cancer, although no studies have examined their associations with prostate cancer risk. Using data from the beta-Carotene and Retinol Efficacy Trial, this nested case-control study examined the relationships between serum phospholipid trans-fatty acids(More)
Several viral transport experiments were conducted in a model aquifer 1 m long, using bacteriophages MS2 and phiX174 at various pH (4.6 to 8.3) conditions, to increase our understanding of virus behavior in ground water. The results indicate the existence of a critical pH at which the virus behavior changes abruptly. This is supported by data from field and(More)
— A method based on differential geometric control theory is presented intended to provide insight into how the nodes of a power network can affect each other. In this preliminary report, we consider a simple model of a power system derived from singular perturbation of the power flow equations. It is shown that such a model is accessible, and that for(More)
Normal aortic endothelial cells cultured in serum-free medium elaborate a factor(s) which cause the proliferation of smooth muscle cells or 3T3 cells grown in medium containing plasma-derived serum. For smooth muscle cell growth plasma factors are required in addition to the endothelial cell-conditioned medium whereas 3T3 cells will grow in the presence of(More)